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Catalase Antibody

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  • 询价
  • Cell Signaling Technology已认证
  • 8841
  • USA
  • 2025年12月19日
  • W
  • Rabbit
  • H,M,R
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 抗体英文名

      Catalase Antibody

    • 抗原

      synthetic peptide corresponding to residues surrounding Ile165 of human catalase protein

    • 应用范围

      W

    • 宿主

      Rabbit

    • 保质期

      详见说明书

    • 供应商

      CST

    • 级别

      详见MSDS文件

    • 库存

      大量

    • 适应物种

      H,M,R

    • 是否单克隆

      2

    • 保存条件

      -20°c

    • 规格

      100 ul (10 western blots)/carrier free & custom formulation / quantity

    规格:产品价格:¥请询价
    规格:100 ul (10 western blots)产品价格:¥请询价
    规格:carrier free & custom formulation / quantity产品价格:¥请询价

    pathway more info application references datasheet PDF MSDS PDF protocols

    Applications Key:  W=Western Blotting
    Reactivity Key:  H=Human  M=Mouse  R=Rat
    Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.

    Applications Reactivity Sensitivity MW (kDa) Source
    W H M R Endogenous 60 Rabbit
    Protocols
    Specificity / Sensitivity

    Catalase Antibody recognizes endogenous levels of total catalase protein.

    Source / Purification

    Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ile165 of human catalase protein. Antibodies are purified by protein A and peptide affinity chromatography.

    Western Blotting

    Western Blotting

    Western blot analysis of extracts from various cell lines using Catalase Antibody.

    Background

    Catalase catalyzes the conversion of hydrogen peroxide to water and oxygen (1). Studies show that overexpression of this antioxidant enzyme increases the ability of pancreatic β-cells to scavenge reactive oxygen species (ROS), thereby protecting pancreatic β-cells from oxidative stress (2). The pancreatic β-cells overexpressing this enzyme are also protected from hydrogen peroxide-mediated lipotoxicity, futher implying the importance of catalase in the pathogenesis of diabetes (3).

    1. Chelikani, P. et al. (2004) Cell Mol Life Sci 61, 192-208.
    2. Chen, H. et al. (2005) Diabetes 54, 1437-46.
    3. Elsner, M. et al. (2011) Diabetes 60, 200-8.
    Application References

    Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know !

    Companion Products

    For Research Use Only. Not For Use In Diagnostic Procedures.

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    图标文献和实验
    相关实验
    • 14 Immunotargeting of Catalase to the Pulmonary Vascular Endothelium

      . In order to provide catalase with such an affinity, catalase could be chemically conjugated with a carrier antibodies recognizing the surface endothelial antigens (8 ). A monoclonal antibody (MAb) against such an antigen, angiotensin-converting enzyme

    • Assays of Sensitivity of Antibiotic-Resistant Bacteria to Hydrogen Peroxide and Measurement of Catalase Activity

      here to measure the viability and relative fitness of bacteria in the presence of hydrogen peroxide. A protocol for the determination of catalase activity, an important part of the ROS detoxification process, is also described.

    • 过氧化氢酶catalase

        催化如下反应的酶: 2H2 O2 —→ 2H2 O O2 。 EC1. 11. 1. 6.另外在 H2 O2 、 CH3 COOH、 C2 H5 -OOH的存在下可将 C2 H5 OH、 CH3 OH、 CH3 CO- OH、 HCOOH、 HNO2 等氧化。因此,在 H2 O2 分解反应中实际上是一部分 H2 O2 分子作为电子供体,另一部分 H2 O2 分子作为电子受体而起反应。根据这一情况, H. Theorell对过

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