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- 详细信息
- 文献和实验
- 技术资料
- 抗体英文名:
Catalase Antibody
- 抗原:
synthetic peptide corresponding to residues surrounding Ile165 of human catalase protein
- 应用范围:
W
- 宿主:
Rabbit
- 保质期:
详见说明书
- 供应商:
CST
- 级别:
详见MSDS文件
- 库存:
大量
- 适应物种:
H,M,R
- 是否单克隆:
2
- 保存条件:
-20°c
- 规格:
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格: | 产品价格: | ¥请询价 | |
|---|---|---|---|
| 规格: | 100 ul (10 western blots) | 产品价格: | ¥请询价 |
| 规格: | carrier free & custom formulation / quantity | 产品价格: | ¥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting
Reactivity Key: H=Human M=Mouse R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Source |
|---|---|---|---|---|
| W | H M R | Endogenous | 60 | Rabbit |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | Catalase Antibody recognizes endogenous levels of total catalase protein. |
| Source / Purification | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ile165 of human catalase protein. Antibodies are purified by protein A and peptide affinity chromatography. |
| Background | Catalase catalyzes the conversion of hydrogen peroxide to water and oxygen (1). Studies show that overexpression of this antioxidant enzyme increases the ability of pancreatic β-cells to scavenge reactive oxygen species (ROS), thereby protecting pancreatic β-cells from oxidative stress (2). The pancreatic β-cells overexpressing this enzyme are also protected from hydrogen peroxide-mediated lipotoxicity, futher implying the importance of catalase in the pathogenesis of diabetes (3). |
| Application References | Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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文献和实验14 Immunotargeting of Catalase to the Pulmonary Vascular Endothelium
. In order to provide catalase with such an affinity, catalase could be chemically conjugated with a carrier antibodies recognizing the surface endothelial antigens (8 ). A monoclonal antibody (MAb) against such an antigen, angiotensin-converting enzyme
here to measure the viability and relative fitness of bacteria in the presence of hydrogen peroxide. A protocol for the determination of catalase activity, an important part of the ROS detoxification process, is also described.
催化如下反应的酶: 2H2 O2 —→ 2H2 O O2 。 EC1. 11. 1. 6.另外在 H2 O2 、 CH3 COOH、 C2 H5 -OOH的存在下可将 C2 H5 OH、 CH3 OH、 CH3 CO- OH、 HCOOH、 HNO2 等氧化。因此,在 H2 O2 分解反应中实际上是一部分 H2 O2 分子作为电子供体,另一部分 H2 O2 分子作为电子受体而起反应。根据这一情况, H. Theorell对过
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