- 询价
- Cell Signaling Technology
- 2009
- USA
- 2025年10月09日
- W, IP
- Rabbit
- H,M,R,X,Z
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 抗体英文名：
Phospho-β-Catenin (Ser33/37) Antibody
- 抗原：
synthetic phosphopeptide corresponding to residues surrounding Ser33 and Ser37 of human β-catenin
- 应用范围：
W, IP
- 宿主：
Rabbit
- 保质期：
详见说明书
- 库存：
大量
- 适应物种：
H,M,R,X,Z
- 级别：
详见MSDS文件
- 供应商：
CST
- 是否单克隆：
2
- 保存条件：
-20°c
- 规格：
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 100 ul (10 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting IP=Immunoprecipitation
Reactivity Key: H=Human M=Mouse R=Rat X=Xenopus Z=Zebrafish
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Source |
|---|---|---|---|---|
| W IP | H (M) (R) (X) (Z) | Endogenous | 92 | Rabbit |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | Phospho-β-Catenin (Ser33/37) Antibody detects endogenous levels of β-catenin only when phosphorylated at Ser33 and Ser37. |
| Source / Purification | Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser33 and Ser37 of human β-catenin. Antibodies are purified by protein A and peptide affinity chromatography. Western Blotting
Western blot analysis of extracts from SW620 cells, untreated or treated with λ phosphatase, using Phospho-β-Catenin (Ser33/37) Antibody. Western Blotting
Western blot analysis of extracts from SW620 cells, untreated or treated with Calyculin A #9902, using Phospho-β-Catenin (Ser33/37) Antibody. |
| Background | β-catenin is a key downstream effector in the Wnt signaling pathway (1). It is implicated in two major biological processes in vertebrates: early embryonic development (2) and tumorigenesis (3). CK1 phosphorylates β-catenin at Ser45. This phosphorylation event primes β-catenin for subsequent phosphorylation by GSK-3 (4-6). GSK-3β destabilizes β-catenin by phosphorylating it at Ser33, Ser37, and Thr41 (7). Mutations at these sites result in the stabilization of β-catenin protein levels and have been found in many tumor cell lines (8).
|
| Application References | Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
