- 询价
- Biological Industries
- SM-0003-0010
- 以色列
- 2025年12月20日
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- 详细信息
- 技术资料
- 细胞类型：
干细胞
- 供应商：
上海逍鹏生物科技有限公司
- 规格：
10 mg
Product Description
Inhibitor of WNT Production-2,
IWP-2 is an inhibitor of the Wnt pathway, specifically targeting membrane-bound O-acyltransferase porcupine (PORCN) with an IC50 of 27 nM. This inhibition, in turn, prevents Wnt activation, secretion, and signaling (Garcia-Reyes, et al.), which leads to decreased self-renewal of human embryonic stem cells (ESCs) (Kim, et al). IWP-2 has been an effective component within differentiation protocols of pluripotent stem cells (PSCs) into functional cardiomyocytes when combined with CHIR99021 (Cat. No. SM-0001-0010), IWP-4 (Cat. No. SM-0004-0005), Activin A, bFGF, and BMP4 (Lian, et al.). Additionally, IWP-2 shows promise in the differentiation of iPSCs into corneal epithelial cells (Mikhailova, et al.).
Product Synonyms:
IWP 2, Inhibitor of WNT Production-2
Constructed from renowned protocols, Biological Industries' selection of small molecules will streamline workflows for research in diabetes, neural disorders, and cardiovascular disease.
产品官网链接：https://www.bioind.com/worldwide/iwp-2/
想了解更多种类的小分子，请点击官网：
https://www.bioind.com/worldwide/products/stem-cell-research/small-molecules/
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