Y27632 (2HCl)

Product Description

Highly potent inhibitor of p160-Rho-associated coiled protein kinase (ROCK),
Y27632 dihydrochloride is a highly specific inhibitor of Rho-associated coiled-coil protein kinase (ROCK) activity as a cell-permeable, ATP-competitive inhibitor of both ROCK1 (Ki of 220 nM) and ROCK2 (Ki 300 nM) (Ishizaki, et al.). Human embryonic stem cell (ESC) survival is improved through enhanced attachment following single cell dissociation and subsequently after FACS analysis or cryopreservation in both feeder-dependent and -independent cultures (Emre, et al.). The enhanced cell attachment and thus recovery is boosted through decreased dissociation-induced apoptosis (Watanabe, et al.).

Product Synonyms:

Y-27632 dihydrochloride, Y-27632, Rock Inhibitor
Constructed from renowned protocols, Biological Industries' selection of small molecules will streamline workflows for research in diabetes, neural disorders, and cardiovascular disease.

产品官网链接：https://www.bioind.com/worldwide/y27632/
想了解更多种类的小分子，请点击官网：https://www.bioind.com/worldwide/products/stem-cell-research/small-molecules/