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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
MHC class I antigen G
- 亚型:
IgG1
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
monoclonal
- 标记物:
Non-conjugated
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Mouse
- 目录编号:
Q9BZJ3
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA, WB, IHC
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
MHC class I antigen G
- 抗体英文名:
HLA-G antibody
- 抗体名:
HLA-G antibody
- 规格:
100μl
HLA-G antibody
Product Name HLA-G antibody
Catalog No PAab09952
Packing 100ul
Form liquid
Alternative Name HLA 6.0, HLA G, HLA G antigen, HLAG, HLA-G, MHC class I antigen G, MHC G
Purification protein A+G purified
Purity 95% as determined by SDS-PAGE
Host Mouse
Isotype IgG1
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). HLA-G is a non-classical MHC class I molecule with multiple immunoregulatory properties. HLA-G exhibits a restricted pattern of expression that includes placental extravillous trophoblasts at the maternal-fetal interface, where it abolishes maternal immune cell activity against fetus and establishes immune tolerance. Aberrant expression of HLA-G has been found in a variety of human neoplastic diseases. It plays an important role in the escape of tumor cells from immunosurveillance.
Immunogen MHC class I antigen G
Specificity Human
Tested Application ELISA, WB, IHC
Recommended dilution WB: 1:2000-1:10000; IHC: 1:50-1:200
IHC use Immunohistochemistry of paraffin-embedded human placenta tissue slide using PAab09952( HLA-G Antibody) at dilution of 1:200
WB use
human placenta tissue were subjected to SDS PAGE followed by western blot with PAab09952( HLA-G Antibody) at dilution of 1:5000
Protein Information
Gene ID 3135
Uniprot ID P17693
Calculated MW 38 kDa
Research Area Immunology
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