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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 免疫原:
CD63 molecule
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9GZT9
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,IHC,WB
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
CD63
- 抗体英文名:
anti-CD63 antibody,CD63 antibody
- 抗体名:
anti-CD63 抗体,CD63 抗体
- 规格:
100μg
CD63抗体| CD63 antibody
货号 PAab01490
蛋白别名 MLA1 antibody, TSPAN30
蛋白介绍
Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.
产品描述
anti-CD63 antibody is a Rabbit Polyclonal antibody againstCD63..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human malignant melanoma tissue slide using PAab01490( CD63 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Western blot
Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with PAab01490( CD63 Antibody) at dilution of 1:1000(本抗体仅供体外科研用途,不可用于临床诊断!)
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- 询问日期
文献和实验CD63 分子 CD63 常用单克隆抗体或代号: RUU- SP2.28,CLB 主要表达细胞: Pt,M,Mac,(G,T,B) [Pt] 分子质量(kDa)和结构: gp53,血小板颗粒蛋白(TM4- SF) 功 能: 血小板活化,中性粒细胞- 活化内皮细胞粘附 CD63 Aka lysosomal-membrane-associated glycoprotein 3, LAMP
在免疫反应方面,基于抗原的刺激在体内形成、并与抗原作特异性结合的蛋白质之总称。其化学实质是免疫球蛋白。抗体,按照抗原抗体反应的类型可分别称为沉淀素、凝集素、溶血素、溶菌素、抗毒素、中和抗体等,但这些并不等于有相应的不同抗体存在,一般多只表明抗体反应的多样性而已。抗体在血清中含量最多(体液抗体=humoral antibody);含有某特定抗体的血清称为抗血或免疫血清。
机体在抗原物质刺激下,由B细胞分化成的浆细胞所产生的、可与相应抗原发生特异性结合反应的免疫球蛋白。因为最初有人用电泳证明血清中抗体活性在γ球蛋白部分,故曾把抗体统称为两种(γ)球蛋白。后来证明,抗体并不都在γ区;而且位于γ区的球蛋白,也不一定都具有抗体活性。1964年,世界卫生组织举行专门会议,将具有抗体活性以及与抗体相关的球蛋白统称为免疫球蛋白(Ig)。如骨髓瘤蛋白,巨球蛋白血症、冷球蛋白血症等患者血清中存在的异常免疫球蛋白以及“正常人”天然存在的免疫
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