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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
PE Anti-Mouse CD115/CSF-1R Antibody流式抗体[AFS98]_货号:E-AB-F1107UD
- 抗体英文名:
PE Anti-Mouse CD115/CSF-1R Antibody[AFS98]_货号:E-AB-F1107UD
- 应用范围:
FCM
- 宿主:
Rat
- 适应物种:
Mouse
- 保质期:
12个月
- 目录编号:
E-AB-F1107UD
- 级别:
科研
- 库存:
999
- 供应商:
武汉伊莱瑞特生物科技股份有限公司
- 标记物:
PE
- 克隆性:
Monoclonal
- 保存条件:
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
- 形态:
液体
- 亚型:
Rat IgG2a, κ
- 规格:
100μg/25μg
| 规格: | 100μg | 产品价格: | ¥2304.0 |
|---|---|---|---|
| 规格: | 25μg | 产品价格: | ¥720.0 |
货号:E-AB-F1107UD
| Background |
CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. This c-fms (Fms proto-oncogene) gene product's natural ligands include M-CSF and IL-34. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitination of intracellular residues. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts.
|
| Alternate Names |
Macrophage colony-stimulating factor 1 receptor;CSF-1 receptor (EC:2.7.10.1);CSF-1-R;CSF-1R;M-CSF-R;Proto-oncogene c-Fms;CD115;Csf1r;Csfmr;Fms;
|
| Swissprot |
P09581
|
| Gene ID |
12978
|
| Clone No |
AFS98
|
| Host |
Rat
|
| Reactivity |
Mouse
|
| Application |
FCM
|
| Isotype |
Rat IgG2a, κ
|
| Isotype Control |
PE Rat IgG2a, κ Isotype Control[2A3]
|
| Conjugation |
PE
|
| Conjugation Information |
PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
|
| Storage Buffer |
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
|
| Storage |
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
|
| Expiration date |
12个月
|
| Shipping |
冰袋
|
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T-cell dependent antigen specific in situ staining (Pe)
6- Wash twice in TBS-T. 7- counterstain with rabbit anti B-Pe 1:2000 (0.5 µg/ml Cortex Biochem). You may add 1% mouse serum to the anti-Pe antibodies, unless you plan to use mouse monoclonal further (see below). 8- wash twice in TBS-T. 9- block
Mouse Strains and Genetic Nomenclature
Beck, J.A., Lloyd, S., Hafezparast, M., Lennon‐Pierce, M., Eppig, J.T., Festing, M.F., and Fisher, E.M. 2000. Genealogies of mouse inbred strains. Nat. Genet. 24:23‐25.
stromal stem cell 。 3 利用流式细胞仪的研究显示,MSCs 属混杂细胞群,其表面抗原也具有非专一性, 它表达了间质细胞、内皮细胞和表皮细胞的表面标志。主要包括: ①黏附分子, 如CD166 、CD54 、CD102 、CD44 、CD106 等。②生长因子和细胞因子受体, 如白介素21 受体( IL-1R ) 、IL-3R 、IL-4R 、IL-6R 、IL-7R 、C 干扰素受体( IFN-CR) 、肿瘤坏死因子(TNF) -A 等。③整合素家族
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