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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
PE anti-mouse CD115 (CSF-1R)
- 抗体英文名:
PE anti-mouse CD115 (CSF-1R)
- 浓度:
0.2 mg/ml
- 应用范围:
免疫荧光,流式
- 宿主:
大鼠
- 供应商:
上海善然生物
- 库存:
现货
- 抗原来源:
大鼠
- 保质期:
2-3年左右
- 适应物种:
小鼠
- 标记物:
PE
- 克隆性:
单克隆
- 保存条件:
2-8度
- 规格:
50ug
PE anti-mouse CD115 (CSF-1R) Antibody
AFS98
Catalog# / Size 135505 / 50 µg
135506 / 200 µg
Clone
Regulatory Status RUO
Other Names CSF-1R, M-CSFR, c-fms
Isotype Rat IgG2a, κ
Description CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and
member of the platelet-derived growth factor receptor family. This c-fms (Fms proto-oncogene)
gene product's natural ligands include M-CSF and IL-34. Structural studies of CD115 have
described an Ig-like extracellular domain, a transmembrane domain, an intracellular
juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor
activation induces homodimerization in addition to phosphorylation and ubiquitination of
intracellular residues. CD115 directly influences tissue macrophage and osteoclast differentiation
and proliferation. It is expressed on monocytes/macrophages, peritoneal exudate cells,
plasmacytoid and conventional dendritic cells, and osteoclasts.
Product Details
Verified Reactivity Mouse
Antibody Type Monoclonal
Host Species Rat
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation The antibody was purified by affinity chromatography, and conjugated with PE under optimal
conditions.
Concentration 0.2 mg/ml
Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged
exposure to light. Do not freeze.
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