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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
PE anti-mouse CD115 (CSF-1R)
- 抗体英文名:
PE anti-mouse CD115 (CSF-1R)
- 浓度:
0.2 mg/ml
- 应用范围:
免疫荧光,流式
- 宿主:
大鼠
- 供应商:
上海善然生物
- 库存:
现货
- 抗原来源:
大鼠
- 保质期:
2-3年左右
- 适应物种:
小鼠
- 标记物:
PE
- 克隆性:
单克隆
- 保存条件:
2-8度
- 规格:
50ug
PE anti-mouse CD115 (CSF-1R) Antibody
AFS98
Catalog# / Size 135505 / 50 µg
135506 / 200 µg
Clone
Regulatory Status RUO
Other Names CSF-1R, M-CSFR, c-fms
Isotype Rat IgG2a, κ
Description CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and
member of the platelet-derived growth factor receptor family. This c-fms (Fms proto-oncogene)
gene product's natural ligands include M-CSF and IL-34. Structural studies of CD115 have
described an Ig-like extracellular domain, a transmembrane domain, an intracellular
juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor
activation induces homodimerization in addition to phosphorylation and ubiquitination of
intracellular residues. CD115 directly influences tissue macrophage and osteoclast differentiation
and proliferation. It is expressed on monocytes/macrophages, peritoneal exudate cells,
plasmacytoid and conventional dendritic cells, and osteoclasts.
Product Details
Verified Reactivity Mouse
Antibody Type Monoclonal
Host Species Rat
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation The antibody was purified by affinity chromatography, and conjugated with PE under optimal
conditions.
Concentration 0.2 mg/ml
Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged
exposure to light. Do not freeze.
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文献和实验更多产品详细信息欢迎来电咨询~周祥15900853496(微信同号),汪海洋15901695283(微信同号)
的。 人IL-3以及IL-4、IL-5、IL-13、GM-CSF、M-CSF、M-CSF受体(c-fms编码产物)、PDGFR(血小板衍生的生长因子受体)、β 2 -肾上腺素能受体(β 2 AR)、内皮细胞生长因子(ECGF)和CD14的基因都定位于第5号染色体。这种在一定区域内连锁的现象可能与协同调节造血过程有关,并可能与骨髓发育异常综合征(myelodysplastic syndrome,MDS)、原发性急性非淋巴细胞白血病(acute
分别利用 CD3 与 CD28 的功能学抗体,以及 CD3/CD28 Streptamer® 激活扩增 T 细胞的实验步骤与实验结果。 CD3/CD28抗体法 1、实验步骤: 1.1 抗体包被 用无菌 PBS 将 anti-mouse CD3 抗体(克隆号:145-2C11)稀释至 5μg/ml,稀释后的抗体加入到 24 孔板中,每孔 400μl,4°C 包被过夜。(注:板子在加入抗体之前,先用无菌 PBS 润洗 2-3 遍,避免干孔); 1.2 小鼠脾脏淋巴细胞分离(次日) 1. 将 70μm
Purification of Immature CD4+CD8+ Thymocytes by Panning with Anti-CD8 Antibody
Most T lymphocytes of the immune system differentiate within the thymus along the CD4/CD8 developmental pathway by a highly ordered process termed thymic selection ( 1 , 2 ). The maturation status of thymocytes is commonly assessed
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