GCG Polyclonal Antibody_货号:E-A

Verified Samples in IHC:Mouse pancreas
Verified Samples in IF:Rat pancreas,Mouse pancreas

IHC 1:500-1:1000, IF 1:200-1:500

Polyclonal

IgG

KLH conjugated Synthetic peptide corresponding to Mouse Glucagon

GCG

GCG;GLP 2;GLP1;GLP2;glucagon;GRPP;Glucagon like peptide 1;GRPP Oxyntomodulin;OXM;Proglucagon抗体

P55095,P06883

Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP-1 and GLP-2 are also secreted in selected neurons in the brain.

1 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Affinity purification

Cancer; Metabolism; Developmental Biology; Signal Transduction; Stem Cells

Unconjugated

The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.