血管紧张素转换酶2,ACE2
Recombinant Human ACE-2 (C419)
产品说明(Description)
Recombinant Human Angiotensin-Converting Enzyme 2 is produced by our Mammalian expression system and the target gene encoding Gln18-Ser740 is expressed with a 6His tag at the C-terminus.
Accession #: Q9BYF1
Known as: Angiotensin-Converting Enzyme 2; ACE-Related Carboxypeptidase; Angiotensin-Converting Enzyme Homolog; ACEH; Metalloprotease MPROT15; ACE2
制剂(Formulation)
Supplied as a 0.2 μm filtered solution of 20mMTris,300mMNacl,1mMZncl2,10%Glycerol,PH7.4.
质量控制(Quality Control)
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin: Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Bioactivity:
Immobilized Human ACE-2-His(Cat#C419) at 10μg/ml (100 μl/well) can bind 2019-nCoV S Protein RBD-mFc (Cat#DRA32). The ED50 of Recombinant 2019-nCoV S Protein RBD-mFc (Cat#DRA32) is 62 ng/ml .
保存(Storage)
Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles.
背景(Background)
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
新冠病毒结合蛋白 |
血管紧张素转换酶2 |
ACE-2 (Mammalian,C-6His) |
C419 |
ACE-2 (Mammalian, C-Fc) |
C05Y |
ACE-2 (Mammalian, C-mFc) |
C06A |
ACE-2 (Mammalian, C-Avi-6His) |
CY51 |
新冠病毒侵入 相关蛋白酶 |
组织蛋白酶Cathepsin |
Cathepsin B (Mammalian,C-6His) |
C398 |
Cathepsin B (Mouse,Mammalian,C-6His) |
CJ65 |
Cathepsin L (Mammalian,C-6His) |
C401 |
Cathepsin L (Mouse,Mammalian,C-6His) |
CX24 |
新冠病毒RNA疫苗 相关产品 |
加帽酶(RNA加帽) |
Vaccinia Capping System |
M062-YH01 |
T7 RNA聚合酶 |
T7 RNA Polymerase |
E121 |
RNA酶抑制剂 |
RNase Inhibitor |
E125 |
脱氧核糖核酸酶I |
DNase I |
E127 |
无机焦磷酸酶 |
Thermostable Inorganic Pyrophosphatase |
M031 |
Pyrophosphatase, Inorganic (E.coli) |
M034 |
Pyrophosphatase, Inorganic (yeast) |
M036 |