- ￥3480
- AntibodySystem
- France
- EHK60701
- 2025年07月14日
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- 文献和实验
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- 保存条件：
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
- 保质期：
1 year
- 英文名：
Recombinant Human CRBN & DDB1 Protein, N-Strep & C-His
- 库存：
999
- 供应商：
AntibodySystem
- 规格：
100ug
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 内毒素水平 | Please contact with the lab for this information. |
| 表达系统 | Insect Cells |
| Accession号 | Q96SW2 & Q16531 |
| 蛋白长度 | CRBN [Glu40-Leu442] & DDB1 [Met1-His1140] |
| 性质 | Recombinant |
| 预测分子量 | 47.73 kDa & 127.93 kDa |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 重悬 | Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details. |
| 别名 | Protein cereblon, CRBN, XAP-1, XPE-binding factor, DNA damage-binding protein a, XAP1, Xeroderma pigmentosum group E-complementing protein, DDB1, XPCe, DDBa, XPE-BF, DDB p127 subunit, Damage-specific DNA-binding protein 1, UV-DDB 1, UV-damaged DNA-binding protein 1, UV-damaged DNA-binding factor, DNA damage-binding protein 1, HBV X-associated protein 1 |
| 种属 | Homo sapiens (Human) |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 备注 | For research use only. |
AntibodySystem Laboratories SAS was established in 2019 in France as an independent brand entity focused on the research, development, and production of protein and antibody reagents in the life sciences field. Our mission is to provide high-quality protein and antibody products to life science researchers worldwide. AntibodySystem's extensive product range includes traditional polyclonal antibodies, classic housekeeping antibodies, tag antibodies, high-activity proteins, in vivo functional antibodies, low-background flow cytometry antibodies, high-specificity nanobodies, specialized small molecule antibodies, premium phospho-specific antibodies, DNA/RNA antibodies, PEG antibodies, and more—spanning over ten product series.
Currently, AntibodySystem's product lines cover multiple research areas, including 500 types of viruses and superbugs, parasites, tumors, Alzheimer's disease, Parkinson's disease, hypersensitivity and allergic reactions, immune suppression, and immune activation.
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文献和实验Liu L, Qiu Y, Suo Y, Tong S, Wang Y, Zhang X, Chen L, Huang Y, Zhou H, Zhou H, Dong Z, Yang CG. Discovery of a potent PROTAC degrader for RNA demethylase FTO as antileukemic therapy. Acta Pharm Sin B. 2024 Dec;14(12):5382-5392.
期刊信息： Acta Pharm Sin B. 2024 Dec;14(12):5382-5392.
作者：Liu L, Qiu Y, Suo Y, Tong S, Wang Y, Zhang X, Chen L, Huang Y, Zhou H, Zhou H, Dong Z, Yang CG
标题：Discovery of a potent PROTAC degrader for RNA demethylase FTO as antileukemic therapy.
IF：4.3
引用详情：货号-EHK60701；品名-Recombinant Human CRBN & DDB1 Protein, N-Strep & C-His
Using the scan‐x Web Site to Predict Protein Post‐Translational Modifications
spectrometry data is providing evidence that almost every protein in the cell undergoes some form of post?translational modification. We describe a protocol to use the scan?x Web site to view predicted acetylation sites in the human proteome and predicted
Mutational Analysis of the Human Protein C Gene
The single gene for protein C is located at position q13–q14 on chromosome 2 (1 ). Two groups have described human genomic clones of protein C isolated from phage l charon libraries using cDNA for human protein C as hybridization probes
ChIP protocol for X. laevis Lens1/FoxE3 enhancer
sec. break x 3 times, 20% amplitude with a small tip). Now the length of your chromatin DNA should be 200-1000 bp. (13) Centrifuge for 20 min at 14000 rpm, 4°C. Recover supernatant. This is the soluble sheared chromatin fraction. This can be stored
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