FITC标记的血管紧张素Ⅱ-1型受体抗体

FITC标记的血管紧张素Ⅱ-1型受体抗体

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  • ¥2980
  • LMAI Bio
  • LM-0630R-FITC
  • 中国/美国/欧洲
  • 2025年07月15日
  • IF=1:50-200
  • Human, Mouse, Rat, Cow, Sheep,
  • Human, Mouse, Rat, Cow, Sheep,
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 靶点

      详见说明书

    • 级别

      1

    • 目录编号

      LM-0630R-FITC

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      Anti-Angiotensin II Type 1 Receptor/FITC

    • 抗体名

      Anti-Angiotensin II Type 1 Receptor/FITC

    • 标记物

      FITC标记

    • 宿主

      Human, Mouse, Rat, Cow, Sheep,

    • 适应物种

      Human, Mouse, Rat, Cow, Sheep,

    • 免疫原

      详见说明书

    • 亚型

      IGg

    • 形态

      粉末、液体、冻干粉

    • 应用范围

      IF=1:50-200

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul

    FITC标记的血管紧张素Ⅱ-1型受体抗体
    英文名称 Anti-Angiotensin II Type 1 Receptor/FITC
    中文名称 FITC标记的血管紧张素Ⅱ-1型受体抗体
    别    名 AG2S; Agtr 1; Agtr1; Agtr1a; AGTR1B; Angiotensin II receptor type 1; Angiotensin II type 1 receptor; AT-1B; AT-1r; AT1; At1a; AT1AR; AT1B; AT1BR; AT2R1; AT2R1A; AT2R1B; HAT1R; Type 1 angiotensin II receptor; AGTR1_HUMAN; Type-1 angiotensin II receptor; Angiotensin II type-1 receptor; AT1R; Ang II; Angiotensin II receptor type 1; Angiotensin II type 1 receptor; Angiotensin receptor 1; Angiotensin receptor 1B; AT 1B; AT1; AT1R.  
    规格价格 100ul/2980元 购买        大包装/询价
    说 明 书 100ul  
    研究领域 心血管  细胞生物  细胞膜受体  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Cow, Sheep, 
    产品应用 IF=1:50-200  
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 39kDa
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human AT1R
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    产品介绍 background:
    Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. At least five transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants. [provided by RefSeq].

    Function:
    Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

    Subunit:
    Interacts with MAS1 (Probable). Interacts with ARRB1.

    Subcellular Location:
    Cell membrane; Multi-pass membrane protein.

    Tissue Specificity:
    Liver, lung, adrenal and adrenocortical adenomas.

    Post-translational modifications:
    C-terminal Ser or Thr residues may be phosphorylated.

    DISEASE:
    Renal tubular dysgenesis (RTD) [MIM:267430]: Autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype). Note=The disease is caused by mutations affecting the gene represented in this entry.

    Similarity:
    Belongs to the G-protein coupled receptor 1 family.

    Database links:

    Entrez Gene: 185 Human

    Entrez Gene: 11607 Mouse

    Entrez Gene: 11608 Mouse

    Entrez Gene: 24180 Rat

    Entrez Gene: 81638 Rat

    Omim: 106165 Human

    SwissProt: P30556 Human

    SwissProt: P29754 Mouse

    SwissProt: P29755 Mouse

    SwissProt: P25095 Rat

    SwissProt: P29089 Rat

    Unigene: 477887 Human

    Unigene: 728754 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

    AT1-受体:血管紧张素Ⅱ-1型受体抗体,主要用于心血管病方面的研究。

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