KCNK3 antibody

KCNK3 antibody

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  • ¥1380 - 2200
  • 康朗生物
  • kl-6674R
  • 中国/美国/德国
  • 2025年11月28日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500
  • Rabbit
  • Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Sheep,
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    • 详细信息
    • 技术资料
    • 供应商

      上海康朗生物科技有限公司

    • 库存

      大量

    • 目录编号

      kl-6674R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      12个月

    • 抗体英文名

      KCNK3 antibody

    • 抗体名

      酸敏感钾离子通道蛋白3抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Sheep,

    • 免疫原

      KLH conjugated synthetic peptide derived from human KCNK3:51-150/394 <Extracellular>

    • 亚型

      IgG

    • 形态

      冻干粉或液体

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul 200ul

    KCNK3 antibody
    中文名称 酸敏感钾离子通道蛋白3抗体
    别    名 cTBAK 1; Acid sensitive potassium channel protein TASK 1; Cardiac two pore background K(+) channel; K2p3.1; OAT1; potassium channel, subfamily K, member 3; rTASK; TASK 1; TBAK1; TWIK related acid sensitive K+ channel; Two pore potassium channel KT3.1; KCNK3; TASK; TASK1; PPH4; TASK; TASK-1; TBAK1; KCNK3_HUMAN.  
    规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 100ul  200ul
    研究领域 神经生物学  通道蛋白  细胞膜受体  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Sheep, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 43kDa
    细胞定位 细胞膜 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human KCNK3:51-150/394 <Extracellular>
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    This gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene. [provided by RefSeq, Aug 2008].

    Function:
    pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward.

    Subcellular Location:
    Membrane; Multi-pass membrane protein (Potential).

    Tissue Specificity:
    Widespread expression in adult. Strongest expression in pancreas and placenta. Lower expression in brain, lung, prostate, heart, kidney, uterus, small intestine and colon.

    Similarity:
    Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.

    SWISS:
    O14649

    Gene ID:
    3777

    Database links:

    Entrez Gene: 3777 Human

    Entrez Gene: 16527 Mouse

    Entrez Gene: 29553 Rat

    Omim: 603220 Human

    SwissProt: O14649 Human

    SwissProt: Q53SU2 Human

    SwissProt: O35111 Mouse

    SwissProt: O54912 Rat

    Unigene: 645288 Human

    Unigene: 439936 Mouse

    Unigene: 15536 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 KCNK3 antibody
    Sample: Pancreas (Mouse) Lysate at 40 ug
    Primary: Anti-KCNK3 (bs-6674R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 43 kD
    Observed band size: 43 kD

    KCNK3 antibody
    Sample: Placenta (Mouse) Lysate at 40 ug
    Primary: Anti-KCNK3 (bs-6674R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 43 kD
    Observed band size: 43 kD

    KCNK3 antibody
    Blank control(blue): H9C2 (fixed with 2% paraformaldehyde (10 min)) . 
    Primary Antibody:Rabbit Anti- KCNK3 antibody(bs-6674R), Dilution: 6ug in 100 uL 1X PBS containing 0.5% BSA; 
    Isotype Control Antibody: Rabbit IgG(orange) ,used under the same conditions ); 
    Secondary Antibody: Goat anti-rabbit IgG-FITC(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA.

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