Staurosporine (PKC抑制剂)

Staurosporine is a potent PKCinhibitor for PKCα, PKCγ and PKCη with IC50 of 2 nM, 5 nM and 4 nM, less potent to PKCδ (20 nM), PKCε (73 nM) and little active to PKCζ (1086 nM) Phase 3.