CD171/L1CAM Rabbit pAb(bs-1996R)-50ul/100ul/200ul
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CD171/L1CAM Rabbit pAb(bs-1996

R)-50ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-1996R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-1996R
    英文名称CD171/L1CAM Rabbit pAb
    中文名称神经细胞粘附分子配体1抗体
    英文别名L1CAM_HUMAN; Neural cell adhesion molecule L1; CAML1; MIC5; N-CAM-L1; NCAM-L1; CD171; L1 cell adhesion molecule; S10; HSAS; MASA; SPG1; HSAS1; N-CAM-L1;
    产品应用Flow-Cyt=1μg /test, ELISA=1:5000-10000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human (Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human CD171
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量138 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Neuroscience > Neurology process > Growth and Development > Axonal Guidance Proteins

    Neuroscience > Neurology process > Neurogenesis

    Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Cell Adhesion Molecules > Liver

    亚细胞定位Cell membrane; Single-pass type I membrane protein.
    相似性Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
    Contains 5 fibronectin type-III domains.
    Contains 6 Ig-like C2-type (immunoglobulin-like) domains.
    功能Cell adhesion molecule with an important role in the development of the nervous system. Involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Binds to axonin on neurons.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料L1cam (L1 cell adhesion molecule isoform 1 precursor) is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. [provided by RefSeq].

     

    应用推荐稀释比例
    {Flow-Cyt}{1μg /test}
    {ELISA}{1:5000-10000}

     

    CD171/L1CAM Rabbit pAb(bs-1996
    Antigen: bs-1996P, 0.2ug/100ul
    Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;
    Secondary: HRP conjugated Goat-Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000;
    TMB(C-0024) staining;
    Read the data in MicroplateReader by 450nm.
    CD171/L1CAM Rabbit pAb(bs-1996
    Antigen: bs-1996P, 0.2ug/100ul
    Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;
    Secondary: HRP conjugated Goat Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000;
    TMB(C-0024) staining;
    Read the data in MicroplateReader by 450nm.
    CD171/L1CAM Rabbit pAb(bs-1996
    Blank control(blue): U937(fixed with 2% P‌‌araformaldehyde (10 min)).
    Primary Antibody:Rabbit Anti-CD171 antibody(bs-1996R), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA.
    Isotype Control Antibody: Rabbit IgG(orange), used under the same conditions ).
    Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA.

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    [IF={{ 12.7 }}] {Lu Weicheng. et al. Interorgan communication in neurogenic heterotopic ossification: the role of brain-derived extracellular vesicles. BONE RES. 2024 Feb;12(1):1-16} {IHC,WB} {Rat}

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    文献支持
    CD171/L1CAM Rabbit pAb(bs-1996R)-50ul/100ul/200ul
    ¥1180 - 2800