Sample:
Lane 1: Mouse Brain Lysates
Lane 2: Mouse Cerebellum Lysates
Lane 3: Mouse Lymph Lysates
Lane 4: Rat Brain Lysates
Lane 5: Rat Cerebellum Lysates
Primary: Anti-5HT1A Receptor (bs-1124R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 46kDa
Observed band size: 46kDa
- ￥1180 - 2800
- Bioss
- bs-1124R
- 2025年10月24日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-1124R |
| 英文名称 | 5HT1A Receptor Rabbit pAb |
| 中文名称 | 5-羟色胺受体1A抗体 |
| 英文别名 | 5HT1A Receptor; HTR1A; 5-HTR1A; 5 HT 1A; 5 HT receptor 1A; 5 HT1A; 5 HT1A receptor; 5 hydroxytryptamine(serotonin) receptor 1A; 5 hydroxytryptamine(serotonin) receptor 1A G protein coupled; 5 hydroxytryptamine receptor 1A; 5-HT-1A; 5-HT1A; 5-hydroxytryptamine receptor 1A; 5HT 1A; 5HT 1A receptor; 5HT receptor 1A; 5HT1a; 5HT1A_HUMAN; ADRB2RL1; ADRBRL1; G 21; G protein coupled receptor; G-21; Gpcr 18; Gpcr18; Guanine nucleotide binding regulatory protein-coupled receptor; PFMCD; Serotonin 1A receptor; Serotonin 5HT1A receptor; Serotonin receptor 1A; |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse, Rat (Human, Dog, Horse, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human 5-HTR1A |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 46 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Signal transduction > G protein signaling > GPCR Metabolism > Types of disease > Obesity Neuroscience > Endocrine system > Hypothalamic pituitary adrenal axis Neuroscience > Neurotransmission > Receptors / Channels > GPCR > Serotonin Receptors Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. 5-hydroxytryptamine receptor subfamily. HTR1A sub-subfamily. |
| 功能 | This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012]. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验该产品被引用文献
[IF={{ 5.62 }}] {Zhou, Q. G., et al. "Reactivation of Tert in the medial prefrontal cortex and hippocampus rescues aggression and depression of Tert−/− mice."Translational Psychiatry 6.6 (2016): e836.} {WB} {="Mouse"}
[IF={{ 5.4 }}] {Taotao Li. et al. Rosemary (Rosmarinus officinalis L.) hydrosol based on serotonergic synapse for insomnia. J ETHNOPHARMACOL. 2023 Jul;:116984} {IHC,WB} {Rat}
[IF={{ 4.3 }}] {Jia Honglin. et al. Mechanisms of Senegenin in Regulating Oxidative Stress and Mitochondria Damage for Neuroprotection in Insomnia: Evidence from In Vivo and In Vitro Models. MOL NEUROBIOL. 2025 Jul;:1-16} {IHC,WB} {Rat}
[IF={{ 4.17 }}] {Yeh, C-B., et al. "Calcitonin alleviates hyperalgesia in osteoporotic rats by modulating serotonin transporter activity." Osteoporosis International (2016): 1-10.} {IHC} {="Rat"}
[IF={{ 3.4 }}] {Honglin Jia. et al. Senegenin regulates the mechanism of insomnia through the Keap1/Nrf2/PINK1/Parkin pathway mediated by GAD67. J SLEEP RES. 2024 Oct;:e14354} {IHC,WB} {Rat}
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5HT1A Receptor Rabbit pAb(bs-1124R)-50ul/100ul/200ul
￥1180 - 2800
