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CCL20 Rabbit pAb(bs-1268R)-50u

l/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-1268R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-1268R
    英文名称CCL20 Rabbit pAb
    中文名称巨噬细胞炎性蛋白MIP-3a抗体
    英文别名CCL20_HUMAN; C-C motif chemokine 20; beta-chemokine exodus-1; CC chemokine LARC; Liver and activation-regulated chemokine; Macrophage inflammatory protein 3 alpha(MIP-3-alpha); Small-inducible cytokine A20; CCL20(1-67); CCL20(1-64); CCL20(2-70); CKb4; LARC; ST38; MIP3A; Exodus; MIP-3a; SCYA20; MIP-3-alpha; MIP3α;
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human (Mouse, Rat)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human CCL20
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量8.6 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚基Binds to and activate CCR6.
    亚细胞定位Secreted.
    组织特异性Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels seen in thymus, prostate, testis, small intestine and colon.
    翻译后修饰C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
    相似性Belongs to the intercrine beta (chemokine CC) family.
    功能Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene displays chemotactic activity for lymphocytes and can repress proliferation of myeloid progenitors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

    产品细节图片1
    P‌‌araformaldehyde-fixed, paraffin embedded (human liver carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CCL20) Polyclonal Antibody, Unconjugated (bs-1268R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.

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    图标文献和实验
    该产品被引用文献

    [IF={{ 5.714 }}] {Tianming Li. et al. IL-17D affects the chemokines and chemokine receptors of intestinal epithelial cells under hyperoxia. INT IMMUNOPHARMACOL. 2022 Dec;113:109386} {IHC} {Rat, Human}

    [IF={{ 5 }}] {Chuan Chen. et al. A novel small molecule effectively ameliorates estrogen deficiency-induced osteoporosis by targeting the gut-bone signaling axis. EUR J PHARMACOL. 2023 Sep;954:175868} {IHC} {Mouse}

    [IF={{ 3.401 }}] {Mitchell Corey Sanders. et al. Protecting human amnion and chorion matrices (HACM) during processing: Performance enhancement in a Diabetic Mouse Model and Human Co-culture System. WOUND REPAIR REGEN. 2023 May;:} {IHC} {Mouse}

    [IF={{ 1.06 }}] {Qin, Shan-Yu, et al. "Role and recruitment of Th9 cells in liver cirrhosis patients." Asian Pacific Journal of Tropical Biomedicine (2016).} {IHC} {="Human"}

    [IF={{ 0 }}] {Liu et al. Clara cell 10-kDa protein inhibits T(H)17 responses through modulating dendritic cells in the setting of allergic rhinitis. (2013) J.Allergy.Clin.Immunol. 131:387-94.e1-12} {IHC} {Mouse}

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    文献支持
    CCL20 Rabbit pAb(bs-1268R)-50ul/100ul/200ul
    ¥1180 - 2800