DIRAS3 | ARHI Rabbit pAb(bs-2903R)-50ul/100ul/200ul产品图

DIRAS3 | ARHI Rabbit pAb(bs-29

03R)-50ul/100ul/200ul
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  • ¥1180 - 2800
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  • bs-2903R
  • 2026年10月13日
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    • 规格:

      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-2903R
    英文名称ARHI Rabbit pAb
    中文名称抑癌基因ras同源家族1抗体
    英文别名DIRA3; DIRAS family GTP binding RAS like 3; Distinct subgroup of the Ras family member 3; GTP binding protein Di Ras3; NOEY2; Rho related GTP binding protein RhoI; RHOI; DIRA3_HUMAN.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应 (Human)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human ARHI
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量25 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Oncoproteins/suppressors > Tumor suppressors

    亚细胞定位Cell membrane; Lipid-anchor; Cytoplasmic side (Potential).
    组织特异性Expressed in normal ovarian and breast epithelial cells but not in ovarian and breast cancers.
    相似性Belongs to the small GTPase superfamily. Di-Ras family.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料ARHI contains a highly conserved GTP-binding domain, a putative effector domain distinct from that of RAS and RAP proteins, and a C-terminal membrane localization motif. ARHI mRNA is detected in all normal breast and ovarian epithelial cell cultures tested, as well as in normal ovary, heart, liver, pancreas and brain however ARHI expression is down-regulated in breast and ovarian tumors. Reactivation of ARHI expression in breast cancer cells is associated with increased histone H3 acetylation and decreased lysine 9 methylation of histone H3.

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}
    {ELISA}{1:5000-10000}

     

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    DIRAS3 | ARHI Rabbit pAb(bs-2903R)-50ul/100ul/200ul
    ¥1180 - 2800