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Raf1(Phospho-Ser259) Antibody

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  • Signalway Antibody已认证
  • 11006
  • USA
  • 2025年07月11日
  • WB IHC
  • Rabbit
  • Hu Ms Rt
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    • 技术资料
    • 抗体英文名

      Raf1(Phospho-Ser259) Antibody

    • 靶点

      Raf1

    • 浓度

      1.0mg/ml

    • 应用范围

      WB IHC

    • 宿主

      Rabbit

    • 适应物种

      Hu Ms Rt

    • 克隆性

      Polyclonal

    • 保存条件

      Store at -20℃

    • 形态

      liquid

    • 免疫原

      Peptide sequence around phosphorylation site of serine 259 (S-T-S(p)-T-P) derived from Human Raf1.

    Product Name:
    Raf1(Phospho-Ser259) Antibody

    Host Species:
    Rabbit

    Clonality:
    Polyclonal

    Purification:
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

    Applications:
    WB IHC

    Species Reactivity:
    Hu Ms Rt

    Specificity:
    The antibody detects endogenous level of Raf-1 only when phosphorylated at serine 259.

    Immunogen Type:
    Peptide-KLH

    Immunogen Description:
    Peptide sequence around phosphorylation site of serine 259 (S-T-S(p)-T-P) derived from Human Raf1.

    Target Name:
    Raf1

    Modification:
    Phospho

    Alternative Names:
    C-RAF; C-Raf; CRAF

    Accession No.:
    Swiss-Prot: P04049
    NCBI Protein: NP _002871.1

    Concentration :
    1.0mg/ml

    Images:
    产品细节图片1

    Western blot analysis of extracts from 293 and MDA cells untreated or treated with PMA using Raf1(Phospho-Ser259) Antibody #11006.
    产品细节图片2
    Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Raf1(Phospho-Ser259) Antibody #11006.

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      该产品被引用文献
      Baicalin induces cellular senescence in human colon cancer cells via upregulation of DEPP and the activation of Ras/Raf/MEK/ERK signaling.Incell Death Dis. On 2018 Feb 13 by Wang Z, Ma L et al..PMID:29440765, , (2018),
      PMID: 29440765


      Mycoplasma ovipneumoniae induces sheep airway epithelial cell apoptosis through an ERK signalling-mediated mitochondria pathway. In BMC Microbiol on 2016 Sep 23 by Yanan Li, Zhongjia Jiang,et al..PMID:27663303, , (2016),
      PMID: 27663303


      Effect of Chaihushugan San on Expression of the Raf/mitogen-activated Protein Kinase/Extracellular Signal-Regulated Kinase Pathway in the Hippocampi of Perimenopausal Rats Induced by Immobilization Stress .In J Tradit Chin Med on 2015 Aug by Li Shengqiang, Liang Wenna et al..PMID:26427116, , (2015),
      PMID: 26427116


      Exosomes Derived From Human Mesenchymal Stem Cells Confer Drug Resistance in Gastric Cancer.In Cell Cycle on 2015 Aug 3 by Runbi Ji , Bin Zhang et al..PMID:26091251, , (2015),
      PMID: 26091251
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      资料下载:

      11006.pdf 附 (下载 0 次)

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      Raf1(Phospho-Ser259) Antibody
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