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PDK1(Phospho-Ser241) Antibody

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  • 询价
  • Signalway Antibody已认证
  • 11005
  • USA
  • 2025年07月16日
  • WB IHC IF
  • Rabbit
  • Hu Ms Rt
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    • 技术资料
    • 抗体英文名

      PDK1(Phospho-Ser241) Antibody

    • 靶点

      PDK1

    • 浓度

      1.0mg/ml

    • 应用范围

      WB IHC IF

    • 宿主

      Rabbit

    • 适应物种

      Hu Ms Rt

    • 克隆性

      Polyclonal

    • 保存条件

      Store at -20℃

    • 形态

      liquid

    • 免疫原

      Peptide sequence around phosphorylation site of serine 241 (A-N-S(p)-F-V) derived from Human PDK1.

    Product Name:
    PDK1(Phospho-Ser241) Antibody

    Host Species:
    Rabbit

    Clonality:
    Polyclonal

    Purification:
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

    Applications:
    WB IHC IF

    Species Reactivity:
    Hu Ms Rt

    Specificity:
    The antibody detects endogenous level of PDK1 only when phosphorylated at serine 241.

    Immunogen Type:
    Peptide-KLH

    Immunogen Description:
    Peptide sequence around phosphorylation site of serine 241 (A-N-S(p)-F-V) derived from Human PDK1.

    Target Name:
    PDK1

    Modification:
    Phospho

    Alternative Names:
    PDPK1; PkB kinase; Protein kinase B kinase; hPDK1; kinase PDK1

    Accession No. :
    Swiss-Prot: O15530
    NCBI Protein: NP_002604.1

    Concentration:
    1.0mg/ml

    Images
    产品细节图片1

    Western blot analysis of extracts from 293 and PC12 cells untreated or treated with EGF using PDK1(Phospho-Ser241) Antibody #11005.
    产品细节图片2
    Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using PDK1(Phospho-Ser241) Antibody #11005(left) or the same antibody preincubated with blocking peptide(right).
    产品细节图片3
    Immunofluorescence staining of methanol-fixed Hela cells using PDK1(Phospho-Ser241) Antibody #11005.

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      图标文献和实验
      该产品被引用文献
      Phosphoproteome analysis reveals an important role for glycogen synthase kinase-3 in perfluorododecanoic acid-induced rat liver toxicity. In Toxicol Lett on 2013 Mar 27 by Hongxia Zhang, Junjie Hou, et al..PMID: 23353032, , (2013),
      PMID: 23353032

      Notch-induced hIL-6 production facilitates the maintenance of self-renewal of hCD34+ cord blood cells through the activation of Jak-PI3K-STAT3 pathway. In Am J Pathol on 2012 Jan by Bongkum Choi, Eunyoung Chun, et al..PMID:22062221, , (2012),
      PMID: 22062221


      Dan Liu, Yi Huang, Bojiang Chen
       Activation of Mammalian Target of Rapamycin Pathway Confers Adverse Outcome in Nonsmall Cell Lung Carcinoma. , Cancer, 117(16):3763-3773 (2011),
      PMID: 21387259


      Activation of mammalian target of rapamycin pathway confers adverse outcome in nonsmall cell lung carcinoma†.In Cancer on 2011 Aug 15 by Dan Liu, Yi Huang, et al..PMID:21387259, , (2011),
      PMID: 21387259
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      资料下载:

      11005.pdf 附 (下载 0 次)

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      PDK1(Phospho-Ser241) Antibody
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