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- 详细信息
- 技术资料
- 供应商:
研卉生物
- 英文名:
Angiotensin Fragment 1-7 (acetate)
- 规格:
1mg
Angiotensin Fragment 1-7 (acetate),Angiotensin1-7
Item № 17594
Purity ≥95%
Description
In the renin-angiotensin system, angiotensin I is cleaved by angiotensin-converting enzyme (ACE) to form angiotensin II, which has effects on blood pressure, as well as fluid and electrolyte homeostasis. Angiotensin fragment 1-7 is an angiotensin metabolite that functions as a type 1 angiotensin II receptor agonist whereupon it can control hydroelectrolyte balance and demonstrates vasodilatory and anti-inflammatory actions in opposition to various adverse effects of angiotensin II (Item No. 17150).1 This peptide can be generated by the action of ACE2, a homolog of ACE, on angiotensin II or by the action of neprilysin on angiotensin I.2 It has been studied in the context of ameliorating the symptoms of metabolic syndrome.3,4
Item № 17594
Purity ≥95%
Description
In the renin-angiotensin system, angiotensin I is cleaved by angiotensin-converting enzyme (ACE) to form angiotensin II, which has effects on blood pressure, as well as fluid and electrolyte homeostasis. Angiotensin fragment 1-7 is an angiotensin metabolite that functions as a type 1 angiotensin II receptor agonist whereupon it can control hydroelectrolyte balance and demonstrates vasodilatory and anti-inflammatory actions in opposition to various adverse effects of angiotensin II (Item No. 17150).1 This peptide can be generated by the action of ACE2, a homolog of ACE, on angiotensin II or by the action of neprilysin on angiotensin I.2 It has been studied in the context of ameliorating the symptoms of metabolic syndrome.3,4
Technical Information
| Formal Name | 5-L-isoleucine-1-7-angiotensin II |
| Molecular Formula | C41H62N12O11 • XC2H4O2 |
| Formula Weight | 899.0 |
| Purity | ≥95% |
| Formulation | A crystalline solid |
| SMILES | O=C([C@H](CC1=CNC=N1)NC([C@@]([H])(NC([C@H](CC2=CC=C(C=C2)O)NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)CCCNC(N)=N)=O)C(C)C)=O)=O)[C@H](CC)C)=O)N3CCC[C@H]3C(O)=O.CC(O)=O |
| InChI Code | 1S/C41H62N12O11.C2H4O2/c1-5-22(4)33(38(61)50-29(17-24-19-45-20-47-24)39(62)53-15-7-9-30(53)40(63)64)52-36(59)28(16-23-10-12-25(54)13-11-23)49-37(60)32(21(2)3)51-35(58)27(8-6-14-46-41(43)44)48-34(57)26(42)18-31(55)56;1-2(3)4/h10-13,19-22,26-30,3 |
| InChI Key | VJHCETPHKAQOHY-LBGFTJIYSA-N |
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Angiotensin1-7
¥750






