Angiotensin Fragment 1-7 (acetate),Angiotensin1-7
Item № 17594
Purity ≥95%
Description
In the renin-angiotensin system, angiotensin I is cleaved by angiotensin-converting enzyme (ACE) to form angiotensin II, which has effects on blood pressure, as well as fluid and electrolyte homeostasis. Angiotensin fragment 1-7 is an angiotensin metabolite that functions as a type 1 angiotensin II receptor agonist whereupon it can control hydroelectrolyte balance and demonstrates vasodilatory and anti-inflammatory actions in opposition to various adverse effects of angiotensin II (Item No. 17150).1 This peptide can be generated by the action of ACE2, a homolog of ACE, on angiotensin II or by the action of neprilysin on angiotensin I.2 It has been studied in the context of ameliorating the symptoms of metabolic syndrome.3,4