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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件:
-20℃ to -80℃
- 保质期:
12个月
- 英文名:
Recombinant Human HMGB1 / HMG1 Protein (Fc Tag)
- 库存:
99
- 供应商:
北京义翘神州科技股份有限公司
- 规格:
20.00 µg/50.00 µg/500.00 µg
| 规格: | 20.00 µg | 产品价格: | ¥2310.0 |
|---|---|---|---|
| 规格: | 50.00 µg | 产品价格: | ¥3220.0 |
| 规格: | 500.00 µg | 产品价格: | ¥16740.0 |
蛋白名称:Human HMGB1 / HMG1 Protein (Fc Tag)
蛋白构建:A DNA sequence encoding the human HMGB1 protein (NP_002119.1) (Met 1-Glu 215) was expressed with the fused Fc region of human IgG1 at the N-terminus.
表达宿主:HEK293 Cells
蛋白纯度:> 97 % as determined by SDS-PAGE
蛋白活性:Measured by its binding ability in a functional ELISA . Immobilized recombinant mouse AGER at 2 μg/ml (100 μl/well) can bind human HMGB1. The EC50 of human HMGB1 is 0.23 μg/ml .
蛋白内毒素:< 1.0 EU per μg of the protein as determined by the LAL method
预测N端:Glu
蛋白分子量:The recombinant human HMGB1/Fc is a disulfide-linked homodimeric protein.The reduced monomer consists of 452 amino acids and has a predictedmolecular mass of 51.5 kDa. As a result of glycosylation, the apparent molecular mass of rhHMGB1/Fc monomer is approximately 55-60 kDa inSDS-PAGE under reducing conditions.
蛋白NP号:NP_002119.1
蛋白氨基酸序列:Met1-Glu215
蛋白标签:N-human IgG1-Fc
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验2, Wu M, et al. Identification of a novel small-molecule inhibitor targeting TIM-3 for cancer immunotherapy.Biochemical pharmacology, PubMed ID: 37148978
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