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50 µg
蛋白名称:IL21 Receptor蛋白, IL21 Receptor protein
蛋白构建:A DNA sequence encoding the rat IL21R (Q5EBB1) (Met1-Pro236) was fused with Fc region of mouse IgG at the C-terminus.
表达宿主:HEK293 Cells
蛋白纯度:> 90 % as determined by SDS-PAGE
蛋白活性:0
蛋白内毒素:< 1.0 EU per μg of the protein as determined by the LAL method
预测N端:Cys 20
蛋白分子量:The recombinant rat IL21R comprises 451 amino acids and has a predicted molecular mass of 51.4 kDa.
蛋白NP号:Q5EBB1
蛋白氨基酸序列:Met1-Pro236
蛋白标签:C-mouse IgG1-Fc
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验为对兔疫球蛋白Fc部分c末端的受体。对具有该受体的细胞,通过抗体与抗原结合时,细胞将发挥如下的特有机能:(1)原噬菌体对IgG,占多形核白细胞大部分的嗜中性细胞对IgG、IgA具有Fc受体,通常通过与抗原结合的抗体以及有时与游离的抗体(嗜细胞性抗体)结合来捕捉抗原,并经吞噬作用将之围吞。(2)B细胞的大部分(80%以上)具有对IgG的Fc受体,这些都不进行产生抗体的细胞分化,可通过与抗原抗体复合体的结合而被活化,释放产生抗体的细胞限制因子。(3)T细胞约有10%具有Fc受体,主要
Analysis of Function of Receptor-G-Protein and Receptor-RGS Fusion Proteins
in detail. The process of fusing the two components, the receptor and the G-protein α-subunit, result in a construct that acts as an agonist stimulated GTPase enzyme whose expression level can be accurately determined by radioligand binding. The effects of different
G Protein-Coupled Receptor Pharmacogenetics
Common G protein-coupled receptor (GPCR) gene variants that encode receptor proteins with a distinct sequence may alter drug efficacy without always resulting in a disease phenotype. GPCR genetic loci harbor numerous variants, such as DNA
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