- ￥3870
- Sino Biological
- 北京
- 80448-R08H
- 2025年08月12日
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- 文献和实验
- 技术资料
- 保存条件：
在-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Recombinant Rat PD1 / PDCD1 / CD279 Protein (His Tag, ECD)
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
100 µg
重组大鼠 PD1 / PDCD1 / CD279 蛋白 (His标签, ECD)（产品说明）
蛋白名称：Rat PD1 / PDCD1 / CD279 Protein (His Tag, ECD)
蛋白构建：A DNA sequence encoding the rat PDCD1 (NP_001100397.1) (Met1-Gln167) was expressed with a polyhistidine tag at the C-terminus.
表达宿主：HEK293 Cells
蛋白纯度：> 95 % as determined by SDS-PAGE.
蛋白活性：Measured by its binding ability in a functional ELISA. Immobilized rat PDCD1-His at 10 μg/ml (100 μl/well) can bind rat CD274-Fc(Cat：80450-R02H), The EC50 of rat CD274-Fc(Cat：80450-R02H) is 40-80ng/ml.
蛋白内毒素：< 1.0 EU per μg protein as determined by the LAL method.
预测N端：Leu 25
蛋白分子量：The recombinant rat PDCD1 consists of 154 amino acids and predicts a molecular mass of 17.7 kDa. It migrates as an approximately 34.8 kDa band in SDS-PAGE under reducing conditions.
蛋白NP号：NP_001100397.1
蛋白氨基酸序列：Met1-Gln167
蛋白标签：C-His
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验1, DeAngelis, N; et al. Discovery and pharmacological characterization of cetrelimab (JNJ-63723283), an anti-programmed cell death protein-1 (PD-1) antibody, in human cancer models. Cancer chemotherapy and pharmacology, Pubmed: 35298699
2, Smith, HG; et al. RIPK1-mediated immunogenic cell death promotes anti-tumour immunity against soft-tissue sarcoma. EMBO Mol Med, Pubmed: 32419365
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