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- GMP-10014-HNAE
- 2026年01月26日
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- 详细信息
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- 文献和实验
- 技术资料
- 英文名：
FGF2 Protein, Human, Recombinant
- 库存：
大量
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
20µg/100µg/1mg/20 µg/100 µg/1 mg
| 规格： | 20µg | 产品价格： | ￥1680.0 |
|---|---|---|---|
| 规格： | 100µg | 产品价格： | ￥4680.0 |
| 规格： | 1mg | 产品价格： | ￥16800.0 |
| 规格： | 20 µg | 产品价格： | ￥780 |
| 规格： | 100 µg | 产品价格： | ￥2080 |
| 规格： | 1 mg | 产品价格： | ￥19800 |
- 纯度：≥ 95 % as determined by SDS-PAGE.
- 内毒素：< 10 EU per mg protein.
- 生物活性：Measured in a cell proliferation assay using Balb/c 3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 0.01-0.1 ng/mL. The specific activity of Recombinant Human FGF basic/FGF2 GMP is >1,000 IU/μg, which is calibrated against the human FGF basic/FGF2 WHO International Standard (NIBSC code: 90/712).
- 蛋白构建：A DNA sequence encoding the human FGF2 (NP_001997.5) (Pro143-Ser288) was expressed.
- 表达宿主：E.coli
- 种属：Human
- 预测 N 端：Met
- 分子量：The recombinant human FGF2 consists of 147 amino acids and predicts a molecular mass of 16.54 kDa.
- 缓冲液
- Supplied as sterile PBS, pH 7.4.
- Please contact us for any concerns or special requirements.
- Please refer to the specific buffer information in the hard copy of CoA.
- 运输方式：Liquid. It is shipped out with blue ice.
- 稳定性 & 储存条件
- Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
- Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
- 复溶：A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
BFGF Protein, Human; FGF-2 Protein, Human; FGFB Protein, Human; HBGF-2 Protein, Human
FGF2 背景信息
Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in remodeling damaged tissue, such as ulcer healing, vascular repair, traumatic brain injury (TBI). bFGF is a critical component of human embryonic stem cell culture medium. In addition, bFGF protein is a heparin-binding cationic protein involved in a variety of pathological conditions including angiogenesis and solid tumour growth. Thus, bFGF is regarded as a target for cancers chemopreventive and therapeutic strategies.
bFGF/FGF2 Protein & Antibody Products
全称
fibroblast growth factor 2 (basic)
研究领域
Cancer Drug Targets
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文献和实验- Takayama S,et al. (2001) Periodontal regeneration by FGF-2 (bFGF) in primate models. J Dent Res. 80(12): 2075-9.
- Niu YJ, et al. (2004) Therapeutic effect of bFGF on retina ischemia-reperfusion injury. Chin Med J (Engl). 117(2): 252-7.
- Zhang Y,et al. (2004) Expression of aFGF, bFGF, and FGFR1 in ovarian epithelial neoplasm. Chin Med J (Engl). 117(4): 601-3.
植物源重组人胰岛素生长因子融合蛋白（OsrIGF-1），胰岛素在无血清细胞培养中的最佳替代品。 IGFs家族由两种低分子多肽(IGF-Ⅰ、IGF-Ⅱ)、两类特异性受体及六种结合蛋白组成。IGF-Ⅰ是一个有70个氨基酸的单链碱性蛋白，分子量7649Da，耐热。IGFs的生物学功能不只局限于有丝分裂刺激作用，它们也能诱导分化或促进分化功能的表达。全新推出的植物源重组人类胰岛素生长因子-1融合蛋白（OsrIGF-1）在IGF-1的N末端融合了人血清白蛋白（HSA），HSA作为蛋白质保护剂增加了IGF
Clinical Trials of GMP Products in the Gene Therapy Field
Advances in gene therapy are increasingly leading to clinical assessment in many fields of medicine with diverse approaches. The basic science stems from approaches aimed at different functions such as correcting a missing/abnormal gene
IJMS:利用转基因水稻种子表达功能性重组人碱性成纤维细胞生长因子
Journal of Molecular Sciences》。 该研究表明通过转基因水稻产生的重组人碱性成纤维细胞生长因子与商业化的重组人碱性成纤维细胞生长因子的功能活性基本一致，例如在促进NIH/3T3细胞增殖以及体外伤口愈合治疗中的活性一致。这项研究再次证明了利用水稻胚乳体系表达各种生物医药蛋白是非常有前景的。 碱性成纤维细胞生长因子（FGF-2）是成纤维细胞生长因子家族中非常重要的成员。由于碱性成纤维细胞生长因子能促进细胞的增殖，其在临床中的烧伤和伤口的愈合治疗中有着非常广泛
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