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- 用户评价
- 文献和实验
- 技术资料
- 英文名:
FGF2 Protein, Human, Recombinant
- 库存:
大量
- 供应商:
北京义翘神州科技股份有限公司
- 规格:
20µg/100µg/1mg/20 µg/100 µg/1 mg
| 规格: | 20µg | 产品价格: | ¥1680.0 |
|---|---|---|---|
| 规格: | 100µg | 产品价格: | ¥4680.0 |
| 规格: | 1mg | 产品价格: | ¥16800.0 |
| 规格: | 20 µg | 产品价格: | ¥780 |
| 规格: | 100 µg | 产品价格: | ¥2080 |
| 规格: | 1 mg | 产品价格: | ¥19800 |
- 纯度:≥ 95 % as determined by SDS-PAGE.
- 内毒素:< 10 EU per mg protein.
- 生物活性:Measured in a cell proliferation assay using Balb/c 3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 0.01-0.1 ng/mL. The specific activity of Recombinant Human FGF basic/FGF2 GMP is >1,000 IU/μg, which is calibrated against the human FGF basic/FGF2 WHO International Standard (NIBSC code: 90/712).
- 蛋白构建:A DNA sequence encoding the human FGF2 (NP_001997.5) (Pro143-Ser288) was expressed.
- 表达宿主:E.coli
- 种属:Human
- 预测 N 端:Met
- 分子量:The recombinant human FGF2 consists of 147 amino acids and predicts a molecular mass of 16.54 kDa.
- 缓冲液
- Supplied as sterile PBS, pH 7.4.
- Please contact us for any concerns or special requirements.
- Please refer to the specific buffer information in the hard copy of CoA.
- 运输方式:Liquid. It is shipped out with blue ice.
- 稳定性 & 储存条件
- Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
- Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
- 复溶:A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
BFGF Protein, Human; FGF-2 Protein, Human; FGFB Protein, Human; HBGF-2 Protein, Human
FGF2 背景信息
Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in remodeling damaged tissue, such as ulcer healing, vascular repair, traumatic brain injury (TBI). bFGF is a critical component of human embryonic stem cell culture medium. In addition, bFGF protein is a heparin-binding cationic protein involved in a variety of pathological conditions including angiogenesis and solid tumour growth. Thus, bFGF is regarded as a target for cancers chemopreventive and therapeutic strategies.
bFGF/FGF2 Protein & Antibody Products
全称
fibroblast growth factor 2 (basic)
研究领域
Cancer Drug Targets
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文献和实验- Takayama S,et al. (2001) Periodontal regeneration by FGF-2 (bFGF) in primate models. J Dent Res. 80(12): 2075-9.
- Niu YJ, et al. (2004) Therapeutic effect of bFGF on retina ischemia-reperfusion injury. Chin Med J (Engl). 117(2): 252-7.
- Zhang Y,et al. (2004) Expression of aFGF, bFGF, and FGFR1 in ovarian epithelial neoplasm. Chin Med J (Engl). 117(4): 601-3.
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干细胞扩增培养组分[2] 2.诱导多能干细胞(iPSC)向HSC分化 联合SCF、TPO、FGF basic、VEGF165等因子,可显著促进iPSC分化为造血干细胞样细胞(HSPC),高表达CD34、CD45等造血干细胞标志物,为再生医学、造血功能障碍治疗提供新的细胞来源。 图4.iPSC向红细胞的分化[3] 3.树突状细胞(DC)疫苗制备 DC细胞是肿瘤免疫治疗的核心抗原呈递细胞,在体外培养体系中添加GMP级重组人FLT3L,可高效扩增DC细胞前体,诱导DC细胞成熟
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