- ￥780 - 45370
- Sino Biological
- 北京
- 11682-HNCH
- 2025年08月12日
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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件：
-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Recombinant Human RANKL / OPGL / TNFSF11 / CD254 Protein
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
1.00 mg/5.00 µg/20.00 µg/50.00 µg/100.00 µg/500.00 µg
| 规格： | 1.00 mg | 产品价格： | ￥45370.0 |
|---|---|---|---|
| 规格： | 5.00 µg | 产品价格： | ￥780.0 |
| 规格： | 20.00 µg | 产品价格： | ￥1780.0 |
| 规格： | 50.00 µg | 产品价格： | ￥2980.0 |
| 规格： | 100.00 µg | 产品价格： | ￥6980.0 |
| 规格： | 500.00 µg | 产品价格： | ￥19380.0 |
蛋白名称：Human RANKL / OPGL / TNFSF11 / CD254 Protein
蛋白构建：A DNA sequence encoding the human TNFSF11 (AAC51762.1) (Gly64-Asp245) was expressed.
表达宿主：HEK293 Cells
蛋白纯度：> 85 % as determined by SDS-PAGE
蛋白活性：1. Immobilized human TNFSF11 (Cat: 11682-HNCH)at 2 μg/ml (100 μl/well) can bind human Osteoprotegerin hFc(Cat: 10271-H02B), The EC50 of human Osteoprotegerin hFc(Cat: 10271-H02B) is 5-40 ng/ml. 2. The bioactivity of hRANKL was determined by measuring the ability of hRANKL to induce TRAP activity in Raw 264.7 cells. The ED50 for this effect is typically 1.5-7.5 ng/mL.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Gly 64
蛋白分子量：The recombinant human TNFSF11 consists of 182 amino acids and has a calculated molecular mass of 20.5 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of the protein is approximately 27 kDa due to the glycosylation.
蛋白NP号：AAC51762.1
蛋白氨基酸序列：Gly64-Asp245
蛋白标签：N-cleavage
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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- 作者
- 内容
- 询问日期
文献和实验2, Nguyen J, et al. A Synthetic Peptide, CK2.3, Inhibits RANKL-Induced Osteoclastogenesis through BMPRIa and ERK Signaling Pathway.Journal of developmental biology, PubMed ID: 32660129
3, Zhao Y, et al. Tumor necrosis factor alpha delivers exogenous inflammation-related microRNAs to recipient cells with functional targeting capabilities.Molecular therapy : the journal of the American Society of Gene Therapy, PubMed ID: 35791880
Clonality - X Chromosome Inactivation Assay
and can assist in interpretation of allele patterns. 4. References Allen RC, Zoghbi HY, Moseley AB, Rosenblatt HM, Belmont JW. Methylation of HpaII and HhaI sites near the polymorphic CAG repeat in the human androgen-receptor gene correlates with X chromosome
. In addition, certain subclasses of rat IgG have been found to interact efficiently with human Fc receptors and the human complement system. More important perhaps in practical terms is that, when grown as an ascites, up to 30 mL of fluid containing 1–5 mg/mL
Ligand- and Structure-Based Pregnane X Receptor Models
The human pregnane X receptor (PXR) is a ligand dependent transcription factor that can be activated by structurally diverse agonists including steroid hormones, bile acids, herbal drugs, and prescription medications. PXR regulates
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