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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件:
-20℃ to -80℃
- 保质期:
12个月
- 英文名:
Recombinant Human RANKL / OPGL / TNFSF11 / CD254 Protein
- 库存:
99
- 供应商:
北京义翘神州科技股份有限公司
- 规格:
1.00 mg/5.00 µg/20.00 µg/50.00 µg/100.00 µg/500.00 µg
| 规格: | 1.00 mg | 产品价格: | ¥45370.0 |
|---|---|---|---|
| 规格: | 5.00 µg | 产品价格: | ¥780.0 |
| 规格: | 20.00 µg | 产品价格: | ¥1780.0 |
| 规格: | 50.00 µg | 产品价格: | ¥2980.0 |
| 规格: | 100.00 µg | 产品价格: | ¥6980.0 |
| 规格: | 500.00 µg | 产品价格: | ¥19380.0 |
蛋白名称:Human RANKL / OPGL / TNFSF11 / CD254 Protein
蛋白构建:A DNA sequence encoding the human TNFSF11 (AAC51762.1) (Gly64-Asp245) was expressed.
表达宿主:HEK293 Cells
蛋白纯度:> 85 % as determined by SDS-PAGE
蛋白活性:1. Immobilized human TNFSF11 (Cat: 11682-HNCH)at 2 μg/ml (100 μl/well) can bind human Osteoprotegerin hFc(Cat: 10271-H02B), The EC50 of human Osteoprotegerin hFc(Cat: 10271-H02B) is 5-40 ng/ml. 2. The bioactivity of hRANKL was determined by measuring the ability of hRANKL to induce TRAP activity in Raw 264.7 cells. The ED50 for this effect is typically 1.5-7.5 ng/mL.
蛋白内毒素:< 1.0 EU per μg of the protein as determined by the LAL method
预测N端:Gly 64
蛋白分子量:The recombinant human TNFSF11 consists of 182 amino acids and has a calculated molecular mass of 20.5 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of the protein is approximately 27 kDa due to the glycosylation.
蛋白NP号:AAC51762.1
蛋白氨基酸序列:Gly64-Asp245
蛋白标签:N-cleavage
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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- 作者
- 内容
- 询问日期
文献和实验2, Nguyen, J; et al. A Synthetic Peptide, CK2.
3, Inhibits RANKL-Induced Osteoclastogenesis through BMPRIa and ERK Signaling Pathway. Journal of developmental biology, PMID: 32660129
3, Zhao, Y; et al. Tumor necrosis factor alpha delivers exogenous inflammation-related microRNAs to recipient cells with functional targeting capabilities. Molecular therapy : the journal of the American Society of Gene Therapy, PMID: 35791880
4, Wang, Z; et al. Isoginkgetin Inhibits RANKL-induced Osteoclastogenesis and Alleviates Bone Loss. Biochemical pharmacology, PMID: 39613114
状。Langerhans细胞具有CD1,HLA-DR和S-100蛋白等免疫标记。电镜下可见胞浆内有一特殊的细胞器称为Langerhans小体或Birbeck颗粒。这是一种呈杆状的管状结构,中央有一纵形条纹和横行平行排列的周期性条纹,形似一条小拉链。有时一端有泡状膨大似网球拍状。Birbeck颗粒是Langerhans细胞所特有的超微结构特征。 组织细胞增生症X时,增生组织细胞的表型、细胞化学和功能等都与Langerhans细胞非常相似,因此目前认为组织细胞增生症X是Langerhans细胞或其前身的增生
佚名 组织细胞增生症 X(histiocytosis X)包括Letterer-Siwe病,Hand-Schüller-Christian病和骨的嗜酸性肉芽肿(eosinophilic granuloma)3种疾病。这三种疾病的临床表现和病理变化不同。Letterer-Siwe病为急性弥漫性,发展快,常表现为恶性过程;Hand-Schüller
TFsearch TFfact 2、Sp1转录因子是参与真核细胞转录的高度相关锌指蛋白,以细胞和启动子特异性方式通过调控富含GC 启动子的基因表达,参与调节细胞功能如细胞增生、凋亡、分化和肿瘤形成. 有关sp1的综述介绍可下载:http://www.namipan.com/d/1641.pdf/0be61a85bb0cd70f115bf737c36a01f140e2f9f0a0410100 本文由丁香园论坛提供,想了解更多有用的、有意思的前沿资讯以及酷炫的实验
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