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ErbB4 蛋白|ErbB4 protein|ErbB4(Mouse, His Tag)

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  • ¥3870
  • Sino Biological已认证
  • 51064-M08H
  • 2025年08月12日
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    • 文献和实验
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      100 µg

    小鼠 ErbB4蛋白|ErbB4 protein|ErbB4(Mouse, C-His)(产品说明)
    蛋白名称:ErbB4蛋白, ErbB4 protein
    蛋白构建:A DNA sequence encoding the mouse ERBB4 (Q99P91) (Met1-Leu652) was expressed with a C-terminal polyhistidine tag.
    表达宿主:HEK293 Cells
    蛋白纯度:> 95 % as determined by SDS-PAGE
    蛋白活性:Measured by its binding ability in a functional ELISA. Immobilized mouse ERBB4-His at 10 μg/ml (100 μl/well) can bind biotinylated human NRG1 (Cat:11609-H01H2), The EC50 of biotinylated human NRG1 (Cat:11609-H01H2) is 0.55-1.29 μg/ml.
    蛋白内毒素:< 1.0 EU per μg of the protein as determined by the LAL method
    预测N端:Gln 26
    蛋白分子量:The recombinant mouse ERBB4 comprises 638 amino acids and has a predicted molecular mass of 71.5 kDa. The apparent molecular mass of the protein is approximately 113 kDa in SDS-PAGE under reducing conditions due to glycosylation.
    蛋白NP号:Q99P91
    蛋白氨基酸序列:Met1-Leu652
    蛋白标签:C-His
    蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

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    相关实验
    • Modeling Schizophrenia in Neuregulin 1 and ErbB4 Mutant Mice

      . However, genetic studies have recently identified many susceptibility genes of this disorder including neuregulin 1 (NRG1 ) and its receptor ErbB4 . Arguably, relevant mutant mice have provided a unique opportunity to model “schizophrenia” in animals

    • ERBB4 Mutation Analysis: Emerging Molecular Target for Melanoma Treatment

      is the ERBB4 receptor, or HER4, a member of the Erb receptor family, which has recently been shown to be a major oncogenic “driver” in melanoma. Mutated ERBB4 signaling activates both aberrant ERBB4 and PI3K-AKT signal transduction, mediates sensitivity

    • 对比 Strep-tag 与 His-tag 系统异同点?

      质,小分子或是金属。当融合有亲和标签的蛋白通过标签-配体作用结合再层析基质上时,通过洗杂步骤,即可去除掉其他的细胞成分。 为了洗脱所需要的蛋白质,通过改变缓冲液的条件,如pH,或通过竞争亲和标签和配体连接的方法来进行。 但怎样的纯化是较为成功的呢?仅达到所需的质量量级,如毫克级(或克级)即可满足吗? 这些并不简单。质在蛋白纯化中同样尤为重要,比如,就蛋白的生物活性和纯度而言,通常会有所要求。   以下我们来讨论并且比较2种技术: His-tag系统和Strep-tag®系统,都使用了亲和层析法来纯化

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