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- Sino Biological
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- 2025年08月12日
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100 µg
蛋白名称：PANP/C12orf53蛋白, PANP/C12orf53 protein
蛋白构建：A DNA sequence encoding the human C12orf53 (Q8IYJ0-1) (Met1-Pro178) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
表达宿主：HEK293 Cells
蛋白纯度：> 96 % as determined by SDS-PAGE
蛋白活性：0
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Ser 32
蛋白分子量：The recombinant human C12orf53/Fc is a disulfide-linked homodimer. The reduced monomer comprises 388 amino acids and has a predicted molecular mass of 42.3 kDa. The apparent molecular mass of the protein is approximately 53 kDa in SDS-PAGE under reducing conditions.
蛋白NP号：Q8IYJ0-1
蛋白氨基酸序列：Met1-Pro178
蛋白标签：C-human IgG1-Fc
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验Ligand- and Structure-Based Pregnane X Receptor Models
The human pregnane X receptor (PXR) is a ligand dependent transcription factor that can be activated by structurally diverse agonists including steroid hormones, bile acids, herbal drugs, and prescription medications. PXR regulates
Using the scan‐x Web Site to Predict Protein Post‐Translational Modifications
spectrometry data is providing evidence that almost every protein in the cell undergoes some form of post?translational modification. We describe a protocol to use the scan?x Web site to view predicted acetylation sites in the human proteome and predicted
HPV 并不是宫颈癌唯一的「元凶」？这种微生物化身「帮凶」，共同促进癌症发生
E7 类器官，并进行了 qRT-PCR 和免疫印迹分析。结果显示，在没有 HPV E6E7 表达的情况下，沙眼衣原体显著抑制 E2F1 和肿瘤抑制因子 p53（TP53），而共感染导致 TP53 明显减少，但 E2F1 和 RB1 转录本没有显著减少。 与沙眼衣原体感染相反，HPV E6E7 上调 TP53、E2F1 和 RB1 基因表达。无论是否感染 HPV，沙眼衣原体感染 hCEcto 细胞后，总 Rb、pRb（S807/811）、E2F1 和 p53 蛋白减少。然而，E6E7 表达增加 E2F
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