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TGF beta 1重组蛋白|Recombinant Human / Rhesus / Cynomolgus / Canine TGF-beta 1 / TGFB1 Protein

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  • ¥680 - 37960
  • Sino Biological已认证
  • 北京
  • 10804-HNAC
  • 2025年08月12日
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    • 详细信息
    • 询价记录
    • 文献和实验
    • 技术资料
    • 保存条件

      -20℃ to -80℃

    • 保质期

      12个月

    • 英文名

      Recombinant Human / Rhesus / Cynomolgus / Canine TGF-beta 1 / TGFB1 Protein

    • 库存

      99

    • 供应商

      北京义翘神州科技股份有限公司

    • 规格

      1.00 mg/5.00 µg/20.00 µg/100.00 µg/500.00 µg

    规格:1.00 mg产品价格:¥37960.0
    规格:5.00 µg产品价格:¥680.0
    规格:20.00 µg产品价格:¥1980.0
    规格:100.00 µg产品价格:¥4980.0
    规格:500.00 µg产品价格:¥16180.0
    重组人 / 恒河猴 / 食蟹猴 / 狗 TGF-beta 1 / TGFB1 蛋白(产品说明)
    蛋白名称:Human / Rhesus / Cynomolgus / Canine TGF-beta 1 / TGFB1 Protein
    蛋白构建:A DNA sequence encoding the active form of human / rhesus / cynomolgus / canine TGFβ1 (NP_000651.3) (Ala 279-Ser 390) was expressed and purified. Human, Rhesus, cynomolgus and Canine TGFβ1 sequences are identical.
    表达宿主:CHO Stable Cells
    蛋白纯度:> 95 % as determined by SDS-PAGE.
    蛋白活性:Measured by its ability to inhibit cell proliferation of Mv-1-lu mink lung epithelial cells. The ED50 for this effect is typically 0.04-0.2 ng/mL.
    蛋白内毒素:< 1.0 EU per μg of the protein as determined by the LAL method
    预测N端:Ala 279
    蛋白分子量:The recombinant human / rhesus / cynomolgus / canine TGFβ1 consists of 112 amino acids and has a calculated molecular mass of 12.8 kDa. it migrates as an approximately 13 & 26 kDa band in reduced and non-reduced SDS-PAGE respectively, corresponding to the monomer and homodimer.
    蛋白NP号:NP_000651.3
    蛋白氨基酸序列:Ala279-Ser390
    蛋白标签:Native
    蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

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    • 作者
    • 内容
    • 询问日期
    图标文献和实验
    该产品被引用文献
    1, Liu S, et al. Sphingomyelin synthase 1 regulates the epithelial‑to‑mesenchymal transition mediated by the TGF‑β/Smad pathway in MDA‑MB‑231 cells.Molecular medicine reports, PubMed ID: 30535436
    2, Zhang H, et al. Alogliptin alleviates liver fibrosis via suppression of activated hepatic stellate cell.Biochemical and biophysical research communications, PubMed ID: 30797555
    3, Sung NJ, et al. DHA inhibits Gremlin-1-induced epithelial-to-mesenchymal transition via ERK suppression in human breast cancer cells.Bioscience reports, PubMed ID: 32141512
    4, Li C, et al. Oocytes and hypoxanthine orchestrate the G2-M switch mechanism in ovarian granulosa cells.Development (Cambridge, England), PubMed ID: 32620578
    5, Zhang X, et al. Roxithromycin attenuates bleomycin-induced pulmonary fibrosis by targeting senescent cells.Acta pharmacologica Sinica, PubMed ID: 33654217
    6, Xia WP, et al. Knockdown of lncRNA XIST inhibited apoptosis and inflammation in renal fibrosis via microRNA-19b-mediated downregulation of SOX6.Molecular immunology, PubMed ID: 34461493
    7, Wang H, et al. Downregulation of acylglycerol kinase suppresses high glucose-induced endothelial-mesenchymal transition in HRECs through regulating the LPAR1/TGF-β/Notch signaling pathway.Canadian journal of physiology and pharmacology, PubMed ID: 34559978
    8, Dong Y, et al. Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis.Acta pharmacologica Sinica, PubMed ID: 34819618
    9, Zhu P, et al. ZLN005 Alleviates In Vivo and In Vitro Renal Fibrosis via PGC-1α-Mediated Mitochondrial Homeostasis.Pharmaceuticals (Basel, Switzerland), PubMed ID: 35455432
    10, Li Z, et al. Luteolin inhibits the TGF-β signaling pathway to overcome bortezomib resistance in multiple myeloma.Cancer letters, PubMed ID: 36442773
    11, Feng Y, et al. Collagen Triple Helix Repeat Containing 1 Deficiency Protects Against Airway Remodeling and Inflammation in Asthma Models In Vivo and In Vitro.Inflammation, PubMed ID: 36640227
    12, Ren Z, et al. Tissue factor overexpression in triple-negative breast cancer promotes immune evasion by impeding T-cell infiltration and effector function.Cancer letters, PubMed ID: 37192729
    13, Liu N, et al. FOSL2 participates in renal fibrosis via SGK1-mediated epithelial-mesenchymal transition of proximal tubular epithelial cells.Journal of translational internal medicine, PubMed ID: 37662889
    14, Xia W, et al. Knockdown of lncRNA MALAT1 attenuates renal interstitial fibrosis through miR-124-3p/ITGB1 axis.Scientific reports, PubMed ID: 37872392
    15, Cao S, et al. Development of dual-mode ELISA based on ALP-catalyzed APP hydrolysis for IL-6 detection.Journal of pharmaceutical and biomedical analysis, PubMed ID: 37783051
    16, Sanchez S, et al. PIK-III exerts anti-fibrotic effects in activated fibroblasts by regulating p38 activation.PloS one, PubMed ID: 39240940
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    文献支持
    TGF beta 1重组蛋白|Recombinant Human / Rhesus / Cynomolgus / Canine TGF-beta 1 / TGFB1 Protein
    ¥680 - 37960