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- 详细信息
- 技术资料
- 保存条件：
4℃保存
- 保质期：
6个月
- 英文名：
VCAM-1 Monoclonal Antibody
- 库存：
1
- 供应商：
上海信裕
- VCAM-1 Monoclonal Antibody保存于运输说明：
- Store at -20°C.
- 详细信息：
-
Description 
Monoclonal Antibody against VCAM-1 Intended Use **Research Use Only (RUO)**
This product is sold for laboratory research use only, not for human or in-vivo use.Clone P3C4 Form VCAM-1 Monoclonal Antibody Ascites Host Mouse Species Reactivity Human IsoType IgG1 [Ab] 1-2 mg/mL Specificity The P3C4 monoclonal antibody was generated against IL-1β activated human umbilical vein endothelial cells (HUVECs). P3C4, recognizes the vascular cell adhesion molecule-1 expressed on activated endothelial cells. VCAM-1 is the ligand for α4β1 expressed in activated leukocytes and used in extravasation during inflammation. This antibody inhibits VCAM-1 binding by α4β1. When used with another monoclonal antibody directed to an alternative epitope this antibody can be used to capture soluble serum VCAM. Uses VCAM-1 Monoclonal Antibody This antibody is effective in immunoprecipitation (IP), immunofluorescence (IF) and flow cytometry but only on IL-1β activated cells. Suggested Working Dilution The optimal working dilution should be determined for each specific assay condition. - IF: 1:1,000
- IP: 1:1,000
- Flow Cytometry: 1:1,000
Storage Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody. For long-term storage, keep the antibody at -80°C. References Kim JA, Territo MC, Wayner E, Carlos TM, Parhami F, Smith CW, Haberland ME, Fogelman AM, Berliner JA. Partial characterization of leukocyte binding molecules on endothelial cells induced by minimally oxidized LDL. Arterioscler Thromb 14(3):427-433, 1994. Warranty/Conditions Covance products may not be resold or modified for resale without prior written approval. - VCAM-1 Monoclonal Antibody
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VCAM-1 Monoclonal Antibody
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