THOP1抗体

THOP1抗体产品信息

免疫原 :
Recombinant Mouse THOP1 protein (Catalog#50828-M07B)
Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
Produced in rabbits immunized with purified, recombinant Mouse THOP1 (rM THOP1; Catalog#50828-M07B; NP_073144.3; Lys 2-Cys687). THOP1 specific IgG was purified by Mouse THOP1 affinity chromatography.
THOP1抗体 Background
Protein Description Thimet oligopeptidase 1 (THOP1), also known as Thimet oligopeptidase, EC 3.4.24.15, or EP24.15. Human endopeptidase (THOP1) is localized on chromosome 19, which againsts toxic effects of Abeta in the early stages of Alzheimer disease (AD) pathology, and suggest that the observed increase in THOP1 expression might be part of a compensatory defense mechanism of the brain against an increased Abeta load. THOP1 was originally described as a neuropeptide-metabolizing enzyme, highly expressed in the brain, kidneys and neuroendocrine tissue. EP24.15 lacks a typical signal peptide sequence for entry into the secretory pathway and is secreted by cells via an unconventional and unknown mechanism. THOP1/EP24.15 actions are increased in androgen-dependent prostate cancer compared to androgen-independent; augmented by androgen treatment, and inhibited by clinical GnRH analogs.
THOP1抗体相关产品如下：
hz-1851R DUSP1丝裂原活化蛋白激酶磷酸酶-1抗体
hz-1852R DUSP4丝裂原活化蛋白激酶磷酸酶-2抗体
hz-7110R DOCK1细胞质分裂付出蛋白1抗体
hz-12115R DNER脑表皮生长因子跨膜蛋白DNER抗体
hz-9664R DUX3DUX3蛋白抗体
hz-6351R DAP1死亡相关蛋白1抗体
hz-11210R DNAH9轴丝动力蛋白重链9抗体
hz-11249R Phospho-DLP1 (Ser616)磷酸化动力相关蛋白1抗体
hz-1677R DNA Ligase IVDNA连接酶4抗体
hz-9010R DPP6二肽基肽酶6抗体
hz-9058R DHFR二氢叶酸还原酶抗体
hz-9052R DIS3L有丝分裂控制样蛋白DIS3L抗体
hz-9053R DIS3L2有丝分裂控制蛋白样DIS3L2抗体
hz-9054R DOM3ZDOM3Z蛋白抗体
hz-9059R Dishevelled 2蓬乱蛋白2抗体
hz-9060R phospho-Dishevelled 2 (Thr224)磷酸化蓬乱蛋白2抗体
hz-9055R DR1 protein转录下调蛋白1抗体
hz-8573R DHRS2脱氢酶/还原酶家族成员2抗体
hz-8557R DSPP牙本质磷蛋白抗体
hz-9056R Dermokine betaDermokine β蛋白抗体
hz-9057R DPCR1DPCR1蛋白抗体
hz-9638R DERP6表皮乳头源性蛋白6抗体
hz-7928R DUSP7双特异性蛋白磷酸酶7抗体
hz-7910R DUSP26双特异性蛋白磷酸酶26抗体（丝裂原活化蛋白激酶磷酸酶8）
hz-7949R DAO1阿米洛利结合蛋白1抗体
hz-7895R DBF4AS期激酶活化蛋白DBF4A抗体
hz-7796R DSN1着丝粒相关蛋白DSN1抗体
hz-11824R DCDC2双皮层蛋白结构域蛋白DCDC2抗体
hz-11833R DAGLA神经干细胞树突调节蛋白DAGLα抗体
hz-11826R DOK4对接蛋白4抗体
hz-11828R DULLARDDULLARD蛋白抗体
hz-11834R DYRK1A丝氨酸/苏氨酸蛋白激酶MNB抗体
hz-11722R DGCR6无胸腺症相关蛋白DGCR6/迪格奥尔格综合征关键基因6抗体
hz-11732R Doppel朊蛋白DPL抗体
hz-11742R DMPK肌强直性营养不良蛋白激酶抗体
hz-7794R DIS3有丝分裂控制蛋白dis3抗体
hz-11835R DACT1肝癌新基因3蛋白抗体
hz-11836R Dact2Dapper2蛋白抗体
hz-11837R DACT3Dapper3蛋白抗体
hz-11839R DNTNP背神经管核蛋白抗体
hz-11997R DDAH1双甲基精氨酸水解酶1抗体
hz-11455R DCAMKL1丝氨酸/苏氨酸蛋白激酶DCAMKL1抗体
hz-11456R Dscam唐氏综合征细胞粘附分子抗体
hz-6250R DPPL1磷脂酸磷酸酶HTPAP抗体