THOP1抗体

THOP1抗体产品信息免疫原 : Recombinant Mouse THOP1 protein (Catalog#50828-M07B)

Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 : Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : Produced in rabbits immunized with purified, recombinant Mouse THOP1 (rM THOP1; Catalog#50828-M07B; NP_073144.3; Lys 2-Cys687). THOP1 specific IgG was purified by Mouse THOP1 affinity chromatography.
THOP1抗体 Background
Protein Description Thimet oligopeptidase 1 (THOP1), also known as Thimet oligopeptidase, EC 3.4.24.15, or EP24.15. Human endopeptidase (THOP1) is localized on chromosome 19, which againsts toxic effects of Abeta in the early stages of Alzheimer disease (AD) pathology, and suggest that the observed increase in THOP1 expression might be part of a compensatory defense mechanism of the brain against an increased Abeta load. THOP1 was originally described as a neuropeptide-metabolizing enzyme, highly expressed in the brain, kidneys and neuroendocrine tissue. EP24.15 lacks a typical signal peptide sequence for entry into the secretory pathway and is secreted by cells via an unconventional and unknown mechanism. THOP1/EP24.15 actions are increased in androgen-dependent prostate cancer compared to androgen-independent; augmented by androgen treatment, and inhibited by clinical GnRH analogs.
THOP1抗体相关产品如下：xy-3814R UBE2泛素激活酶2（泛素激活酶E1相关蛋白抗体）
xy-4050R UBL7泛素样蛋白7抗体
xy-12378R UCMA软骨基质相关蛋白UCMA抗体
xy-13680R UBXN2BUBXN2B蛋白抗体
xy-2171R URG4上调基因4抗体(N端)
xy-1549R Ubiquitin泛素蛋白抗体
xy-5820R USP28泛素特异性蛋白酶28抗体
xy-1098R Urokinase尿激酶型纤溶酶原激活因子抗体
xy-0603R URAT1/SLC22A11尿酸盐重吸收转运子1抗体
xy-9616R C14orf13014号染色体开放阅读框130抗体
xy-4806R USP3去泛素化酶3抗体
xy-6462R Unc18-3突触囊泡融合蛋白Unc18-3抗体
xy-9144R UBR2泛素蛋白连接酶E3α2抗体
xy-9923R UVRAG肿瘤抑制基因UVRAG抗体
xy-8372R UFC1泛素结合酶UFC1抗体
xy-8374R UBE2J1泛素结合酶E2J1抗体
xy-8298R UQCRC1辅酶细胞色素C还原酶核心蛋白1抗体
xy-6427R UHRF1核蛋白95抗体
xy-7882R UBE2V1泛素结合酶E2变异体1抗体
xy-8375R UBE2A泛素结合酶E2蛋白A抗体
xy-8380R UBE2O泛素结合酶E2O抗体
xy-8381R UBE2J2泛素蛋白连接酶J2抗体
xy-8382R UBE2M泛素蛋白连接酶M抗体
xy-8385R UBE2W泛素蛋白连接酶W抗体
xy-12043R UNCX同源蛋白UNCX抗体
xy-2730R ULBP3UL16结合蛋白3抗体
xy-8611R USP22去泛素化酶22抗体
xy-2362R UBF1RNA聚合酶I抗体
xy-10357R SLC22A11尿酸盐重吸收转运子1抗体
xy-12305R USE1囊泡转运蛋白Use1抗体
xy-6730R Upstream Binding Protein 1上游结合蛋白1抗体
xy-8504R UNC93B内质网膜蛋白UNC93B抗体
xy-11492R UNC5B神经突起诱导因子受体UNC5B抗体
xy-11493R UNC5C神经突起生长诱导因子受体UNC5B抗体