MEP1A抗体

MEP1A抗体产品信息

免疫原 :
Recombinant Mouse MEP1A Protein (Catalog#50057-M08H)
Antibody Type : Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
克隆号 :
001
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
This antibody was obtained from a rabbit immunized with purified, human cell-derived, recombinant Mouse MEP1A (rM MEP1A; Catalog#50057-M08H; NP_032611.2; Met 1 - Arg 615).
MEP1A抗体Background
Meprin A subunit alpha, also known as MEP1A, and Endopeptidase-2, is a single-pass type I membrane protein which belongs to the peptidase M12A family. MEP1A contains one EGF-like domain, one MAM domain, and one MATH domain. Meprins are unique plasma membrane and secreted metalloproteinases that are highly regulated at the transcriptional and post-translational levels. Meprin alpha and beta subunits are abundantly expressed in kidney and intestinal epithelial cells, are secreted into the urinary tract and intestinal lumen, and are found in leukocytes and cancer cells under certain conditions. Meprins are capable of proteolytically degrading extracellular matrix proteins, proteolytically processing bioactive proteins, and play a role in inflammatory processes. Meprin A and B are highly regulated, secreted and cell-surface homo- and hetero-oligomeric enzymes. Meprins are abundantly expressed in kidney and intestine. The multidomain alpha and beta subunits have high sequence identity. They have very different substrate specificities, oligomerization potentials and are differentially regulated. Meprin A appears to be an important therapeutic target and urinary excretion appears to be a potential biomarker of acute kidney injury ( AKI ).
MEP1A抗体相关产品如下：
hz-9356R PSMA7蛋白酶体PSMα7抗体
hz-9612R PIBF1孕酮诱导阻断因子1抗体
hz-9623R PARP16多腺苷二磷酸多聚酶16抗体
hz-9605R PITX2成对样同源结构域转录因子2抗体
hz-6972R RNA polymerase IIRNA聚合酶II抗体
hz-1364R PHLDA1T淋巴细胞凋亡相关蛋白TDAG51抗体
hz-1372R PSMD9蛋白酶调解因子9抗体
hz-8543R Pancreatic hormone胰腺激素抗体
hz-9844R PLGLB2纤溶酶相关蛋白B2抗体
hz-9435R PAPOL A+B+G多聚合酶α/β/γ抗体
hz-11198R ProSAPiP1 含脯氨酸突触相关蛋白相互作用蛋白1抗体
hz-11197R PRPH2外周蛋白2抗体
hz-11176R Pregnancy zone protein妊娠区带蛋白PZP抗体
hz-9548R PGGT1B蛋白香叶烯基转移酶1β（FTβ）抗体
hz-11134R PCDHB15原钙粘蛋白15抗体
hz-11136R PCDHB2原钙粘蛋白β2抗体
hz-11138R PCDHB4原钙粘蛋白β4抗体
hz-11143R PCDHGA10原钙粘蛋白γ10抗体
hz-11144R PCDHGA4原钙粘蛋白γA4抗体
hz-11145R PCDHGA2原钙粘蛋白γA2抗体
hz-11147R PCDHGA5原钙粘蛋白γA5抗体
hz-11148R PCDHGA7原钙粘蛋白γA7抗体
hz-11149R PCDHGA8原钙粘蛋白γA8抗体
hz-11150R PCDHGA9原钙粘蛋白γA9抗体
hz-11151R PCDHGA11原钙粘蛋白γA11抗体
hz-11152R PCDHGA12原钙粘蛋白γA12抗体
hz-11153R PCDHB12原钙粘蛋白β12抗体
hz-11154R PCDHB3原钙粘蛋白β3抗体
hz-11155R PCDHGB1原钙粘蛋白γB1抗体
hz-11156R PCDHGB2原钙粘蛋白γB2抗体
hz-11157R PCDHGB4原钙粘蛋白γB4抗体
hz-11158R PCDHGB6原钙粘蛋白γB6抗体
hz-11159R PCDHGC3原钙粘蛋白γC3抗体
hz-11160R PCDHGC4原钙粘蛋白γC4抗体
hz-11327R PTP zeta磷酸蛋白聚糖PTPRZ抗体
hz-11328R PTPN5/STEP神经特异蛋白酪氨酸磷酸酶N5抗体
hz-8688R POD1足细胞表达蛋白/转录因子21抗体
hz-0183R progesterone receptor孕激素受体抗体
hz-11354R Piccolo神经细胞突触蛋白PCLO抗体
hz-6456R PEN2 早老素γ分泌酶2抗体
hz-8337R PANK1泛酸激酶1抗体
hz-8338R PANK2泛酸激酶2抗体
hz-8339R PANK3泛酸激酶3抗体
hz-8325R PA26p53调控PA26核蛋白抗体
hz-8322R Proteasome 19S S5A26S蛋白酶调节亚型S5a抗体
hz-8328R PP4R3B丝氨酸/苏氨酸蛋白磷酸酶3B抗体
hz-9547R PGGT1A蛋白香叶烯基转移酶1α抗体
hz-4895R PIRH2泛素连接酶抗体
hz-9371R PGBD3PGBD3蛋白抗体