Complement C5a抗体

Complement C5a抗体产品信息

免疫原 :
Recombinant Human Complement C5a Protein (Catalog#10604-HNAE)
Antibody Type : Mouse Monoclonal Antibody ( Mouse mAb Service Platform )
克隆号 :
5E 1D1
抗体宿主 :
Mouse IgG2b
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, human cell-derived, recombinant Human Complement C5a (rh Complement C5a; Catalog#10604-HNAE; Leu 679 - Arg 751). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Complement C5a抗体 Background
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathways of complement activation. The structure of C5a includes a core region consisting of four, anti-parallel alpha-helices held together by three disulfide linkages and a structured C-terminal tail, and C5a is rapidly metabolised by carboxypeptidase B to a 73 amino acid low activity form, C5a des-Arg. C5a is an extremely potent proinflammatory mediator, as well as a potent chemotactic factor for neutrophils and other leukocytes. It causes histamine release, increases in vascular permeability, induces several cytokines production from leukocytes, enhances neutrophil-endothelial cell adhesion, and augments the humoral and cell-mediated immune response. C5a exerts actions by binding to G-protein-coupled receptor (C5aR/CD88) on the plasma membrane of target cells. Accordingly, the anaphylatoxin C5a is implicated in a variety of diseases such as rheumatoid arthritis, systemic lupus erythematosus, reperfusion injury, Alzheimer's disease, and sepsis.
Complement C5a抗体相关产品如下：
hz-15048R C1orf189 1号染色体开放阅读框189抗体
hz-15049R C1ORF1901号染色体开放阅读框190抗体
hz-15051R C1orf1921号染色体开放阅读框192抗体
hz-15052R C1orf1941号染色体开放阅读框194抗体
hz-15054R C1orf1981号染色体开放阅读框198抗体
hz-15057R C1orf211号染色体开放阅读框21抗体
hz-15058R C1orf2161号染色体开放阅读框216抗体
hz-15066R C1orf43 1号染色体开放阅读框43抗体
hz-15068R C1orf501号染色体开放阅读框50抗体
hz-15067R C1orf491号染色体开放阅读框49抗体
hz-15069R C1orf531号染色体开放阅读框53抗体
hz-15070R C1orf541号染色体开放阅读框54抗体
hz-15071R C1orf551号染色体开放阅读框55抗体
hz-15072R C1orf561号染色体开放阅读框56抗体
hz-15074R C1orf651号染色体开放阅读框65抗体
hz-15073R C1orf641号染色体开放阅读框64抗体
hz-15075R C1orf691号染色体开放阅读框69抗体
hz-15076R C1orf771号染色体开放阅读框77抗体
hz-15077R C1orf84 1号染色体开放阅读框84抗体
hz-15405R CHIPE3泛素蛋白连接酶CHIP蛋白抗体
hz-15397R CRAT肉毒碱O-乙酰基转移酶
hz-15206R C5orf455号染色体开放阅读框45抗体
hz-15207R C5orf48 5号染色体开放阅读框48抗体
hz-15219R C6orf1366号染色体开放阅读框136抗体
hz-15220R C6orf1386号染色体开放阅读框138抗体
hz-15222R C6orf1456号染色体开放阅读框145抗体
hz-15383R CD39CD39抗体
hz-15213R C6orf1066号染色体开放阅读框106抗体
hz-15214R C6orf1156号染色体开放阅读框115抗体
hz-15215R C6orf1236号染色体开放阅读框123抗体
hz-15216R C6orf129 6号染色体开放阅读框129抗体
hz-15217R C6orf1306号染色体开放阅读框129抗体
hz-15218R C6orf1326号染色体开放阅读框132抗体
hz-10342R Phospho-Calcineurin B (Tyr106)磷酸化钙调磷酸酶B亚基B1抗体
hz-15409R CYP51A1羊毛甾醇14α-去甲基化酶蛋白抗体
hz-15197R C5 补体C5抗体
hz-15201R C5orf245号染色体开放阅读框24抗体
hz-15204R C5ORF425号染色体开放阅读框42抗体
hz-15208R C5orf495号染色体开放阅读框49抗体
hz-15203R C5orf355号染色体开放阅读框35抗体
hz-13856R CEP192中心体蛋白192抗体
hz-13857R CEP27中心体蛋白27抗体
hz-13858R CEP290中心体蛋白290抗体