Complement C5a抗体

C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathways of complement activation. The structure of C5a includes a core region consisting of four, anti-parallel alpha-helices held together by three disulfide linkages and a structured C-terminal tail, and C5a is rapidly metabolised by carboxypeptidase B to a 73 amino acid low activity form, C5a des-Arg. C5a is an extremely potent proinflammatory mediator, as well as a potent chemotactic factor for neutrophils and other leukocytes. It causes histamine release, increases in vascular permeability, induces several cytokines production from leukocytes, enhances neutrophil-endothelial cell adhesion, and augments the humoral and cell-mediated immune response. C5a exerts actions by binding to G-protein-coupled receptor (C5aR/CD88) on the plasma membrane of target cells. Accordingly, the anaphylatoxin C5a is implicated in a variety of diseases such as rheumatoid arthritis, systemic lupus erythematosus, reperfusion injury, Alzheimer's disease, and sepsis.
Complement C5a抗体相关产品如下：xy-0437xy-Golxy Streptavidin/Gold金标记链霉亲和素(10nm/15nm)
xye-0312xy Avidin/HRP辣根过氧化物酶标记亲合素
xye-0302R Rabbit Anti-HRP/HRP辣根过氧化物酶标记兔抗HRP
xye-0360R Rabbit Anti-human IgA/HRP辣根过氧化物酶标记兔抗人IgA
xye-0362xy Protein A/HRP辣根过氧化物酶标记的蛋白A
xye-0292xy BSA/HRP 辣根过氧化物酶标记牛血清白蛋白
xy-0855xy-HRxy Insulin/HRP辣根过氧化物酶标记人胰岛素蛋白
xy-0311xy-Axy Biotin/AP碱性磷酸酶标记生物素
xy-0312xy-Axy Avidin/AP碱性磷酸酶标记亲合素
xy-0360G-Axy Goat Anti-human IgA/AP碱性磷酸酶标记羊抗人IgA
xy-0360R-Axy Rabbit Anti-human IgA/AP碱性磷酸酶标记兔抗人IgA
xy-0362xy-Axy Protein A/AP碱性磷酸酶标记的蛋白A
xyb-0360G Goat Anti-human IgA/Biotin生物素化羊抗人IgA
xy-0295xy-Bio Rabbit IgG/Biotin生物素化兔IgG
xyb-0296xy mouse IgG/Biotin生物素化小鼠IgG
xyF-0366R Rb Anti-FITC/FITC荧光素标记兔抗FITC
xy-0437xy-RBITxy Streptavidin/RBITC红色荧光素罗丹明标记链霉亲和素
xy-0295xy-RBITxy Rabbit IgG/RBITC罗丹明标记兔IgG(细胞流式同型对照)
xyR-0296xy Mouse IgG/RBITC罗丹明标记小鼠IgG(细胞流式同型对照)
xyR-0294xy Goat IgG/RBITC罗丹明标记羊IgG(细胞流式同型对照)
xyR-0293xy Rat IgG/RBITC罗丹明标记大鼠IgG(细胞流式同型对照)
xyF-0312xy Avidin/FITC荧光素标记亲合素
xy-0437xy-FITxy Streptavidin/FITC 荧光素标记链霉亲和素
xyR-0366R Rb Anti-FITC/RBITC罗丹明标记兔抗FITC
xyR-0360G Goat Anti-human IgA/RBITC罗丹明标记羊抗人IgA
xyR-0312xy Avidin/RBITC罗丹明标记亲合素
xyR-0362xy Protein A/RBITC罗丹明标记蛋白A
xyR-0326xy Bovine IgG/RBITC罗丹明标记牛IgG
xyR-0327xy Bovine IgM/RBITC罗丹明标记牛IgM
xyR-0310xy Chicken IgG/RBITC罗丹明标记鸡IgG
xyR-0314xy Chicken IgM/RBITC罗丹明标记鸡IgM
xyR-0303xy dog IgG/RBITC罗丹明标记狗IgG
xyR-0370xy Goat IgM/RBITC罗丹明标记羊IgM