TGM2 / Transglutaminase 2抗体

TGM2 / Transglutaminase 2抗体产品信息

免疫原 :
Recombinant Human TGM2 / Transglutaminase 2 protein (Catalog#11095-H07B)
Antibody Type : Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
克隆号 :
013
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
This antibody was obtained from a rabbit immunized with purified, recombinant Human TGM2 / Transglutaminase 2 (rh TGM2 / Transglutaminase 2; Catalog#11095-H07B; NP_004604.2; Met 1-Ala 687).
TGM2 / Transglutaminase 2抗体Background
Protein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of thetransglutaminase superfamily. Human TGM2 is implicated in the pathogenesis of several neurodegenerative disorders including Alzheimer's, Parkinson's and expanded polyglutamine (polyQ) diseases. TGM2 promotes formation of soluble and insoluble high molecular weight aggregates by catalyzing a covalent linkage between peptide-bound Q residues in polyQ proteins and a peptide-bound Lys residue. TGM2 plays a role in cell growth and survival through the anti-apoptosis signaling pathway. Its expression is involved with tumor growth. The expression of TGM2 plays an important role in doxorubicin/cisplatin resistance in breast and ovarian cancer. Down-regulation and over-expression of TGM2 in non-small cell lung cancer (NSCLC) cell suggested a positive correlation of cisplatin sensitivity and TGM2 inhibition. Good responders of cisplatin in NSCLC could be identified by the promoter methylation of TGM2. TGM2 is also useful as a predictive marker for patient prognosis and may be a novel therapeutic target for colorectal cancer (CRC).
TGM2 / Transglutaminase 2抗体相关产品如下：
hz-3126R Phospho-EphA2 (Tyr594)磷酸化酪氨酸蛋白激酶A2受体抗体
hz-2764R Ephrin BEphrin B抗体
hz-3217R phospho-Ephrin B (Tyr329)磷酸化Ephrin B抗体
hz-3167R phospho-Ephrin B (Tyr316)磷酸化Ephrin B抗体
hz-3128R phospho-Ephrin B (Ser300)磷酸化Ephrin B抗体
hz-3129R phospho-Ephrin B (Tyr324 + Tyr29)磷酸化Ephrin B抗体
hz-3130R Phospho-Estrogen Receptor alpha (Ser118)磷酸化雌激素受体α抗体
hz-3131R Phospho-Estrogen Receptor alpha (Ser104 + Ser106) 磷酸化雌激素受体α抗体
hz-3848R EPS8表皮生长因子受体底物8抗体
hz-0202R ET-1内皮素1抗体
hz-0852R EV71 polyprotein VP4肠道病毒71型/手足口病病毒抗体
hz-0022R ERK1 + ERK2丝裂原活化蛋白激酶1抗体
hz-1020R ERK1丝裂原活化蛋白激酶3抗体
hz-0122R Estrogen Receptor alpha雌激素受体α抗体
hz-0116R Estrogen receptor beta雌激素受体β 抗体
hz-0593R EpCAM上皮特异性抗原抗体
hz-0188R ET-1内皮素-1抗体
hz-0613R Eukaryotic aspartyl protease天冬氨酸蛋白酶家族蛋白抗体
hz-0602R Echidnotoxin蝮蛇蛇毒蛋白抗体
hz-1001R E2F2转录因子E2F-2抗体
hz-0485R EphA2内皮细胞受体蛋白酪氨酸激酶抗体
hz-0247R EphB2 R酪氨酸蛋白激酶受体B2抗体
hz-0894R Phospho-Estrogen Receptor alpha (Ser167)磷酸化雌激素受体ER alpha 抗体
hz-2194R EGFP重组增强型绿色荧光蛋白抗体
hz-0254R ER-Alpha雌激素受体α抗体（用于western blot）
hz-0174R Estrogen Receptor alpha + beta雌激素受体α/β抗体
hz-2437R Anei-ENPP2自分泌运动因子抗体
hz-6047R Ephrin A3酪氨酸蛋白激酶A3受体抗体
hz-13065R EHM2EHM2蛋白抗体
hz-2446R phospho-eIF4E (Ser209)磷酸化真核翻译起始因子4E抗体
hz-2503R eEF1A1翻译延伸因子EF-1a抗体
hz-1643R Phospho-Estrogen Receptor alpha (Tyr537) 磷酸化雌激素受体α抗体
hz-1644R phospho-EGFR (Tyr1068)磷酸化表皮生长因子受体抗体
hz-1645R phospho-Erk1 (Thr202 + Tyr204) 磷酸化丝裂原活化蛋白激酶1抗体
hz-1646R phospho-ERK1 (Thr202/Tyr204) + ERK2 (Thr183/Tyr185)磷酸化丝裂原活化蛋白激酶1/2抗体
hz-6046R EPHB4酪氨酸蛋白激酶受体B4抗体
hz-6048R Ephrin A5酪氨酸蛋白激酶A5受体抗体
hz-4263R epithelial Sodium Channel gamma上皮钠离子通道蛋白γ/γENaC抗体
hz-5964R ETS2癌基因ETS2抗体
hz-5897R Endothelin 3内皮素3抗体
hz-5484R phospho-ERK5 (Ser496)磷酸化细胞外信号调节激酶5抗体
hz-5486R phospho-ERK5 ( Ser731+Thr733)磷酸化细胞外信号调节激酶5抗体
hz-4131R ERK4细胞外信号调节激酶4抗体