脯氨酸羟化酶抗体

PHD3 (Egl nine homolog 3; Hypoxia-inducible factor prolyl hydroxylase 3; HIF-prolyl hydroxylase 3; HIF-PH3; HPH-1; Egln3; Prolyl hydroxylase domain-containing protein 3;)Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-564', and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. May play a role in cell growth regulation in muscle cells and in apoptosis in neuronal tissue. Promotes cell death through a caspase-dependent mechanism. [Catalytic Activity] An HIF alpha chain L-proline + 2-oxoglutarate+ O(2) = An HIF alpha chain trans-4-hydroxy-L-proline + succinate + CO(2). [Subcellular Location] Cytoplasm. Nucleus. Widely expressed at low levels. Expressed athigher levels in heart (cardiac myocytes, aortic endothelial cells and coronary artery smooth muscle) and placenta.mol wt:26kDa
脯氨酸羟化酶抗体xy-15496R ALDH3A1乙醛脱氢酶家族3成员A1抗体
xy-12963R phospho-alpha B Crystallin (Ser59)磷酸化热休克蛋白β5/αb晶体蛋白质/α-晶体蛋白b链抗体
xy-12368R ACTG2γ2肌动蛋白抗体
xy-12392R AESgp130结合蛋白GAM抗体
xy-12414R AMHR2缪勒激素2型受体抗体
xy-12415R ACTR1激活素受体1A抗体
xy-12416R ACTR2激活素受体2A抗体
xy-12417R Activin Receptor Type IIB激活素受体2B抗体
xy-15163R C2orf88 2号染色体开放阅读框88抗体
xy-7144R ARHGEF18G蛋白偶联受体ARHGEF18抗体
xy-3763R Activin A Receptor Type IB激活素受体1B抗体
xy-3751R ARA24雄激素受体相关蛋白24抗体
xy-0347R Amyloid Precursor Protein淀粉样肽前体蛋白抗体（C端）
xy-3920R ADCY2腺苷酸环化酶2抗体
xy-5037R APOC3载脂蛋白C3抗体
xy-5038R Apolipoprotein E4载脂蛋白E4抗体
xy-3830R AMBRA1自噬相关基因AMBRA1抗体
xy-5200R Phospho-ATG4C(Ser177)磷酸化自噬相关蛋白4C抗体
xy-5205R Phospho-ATG4C(Ser398)磷酸化自噬相关蛋白4C抗体
xy-3007R phospho-ASK1 (Ser966)磷酸化细胞凋亡信号调节激酶1抗体
xy-3008R phospho-ATXN1 (Ser775)磷酸化失调症蛋白1抗体
xy-2732R ATXN1/Ataxin-1脊髓小脑失调症蛋白1抗体
xy-3028R phospho-Amyloid Precursor Protein (Thr668)磷酸化APP淀粉样肽前体蛋白抗体
xy-3029R phospho-ASK1 (Ser967)磷酸化细胞凋亡信号调节激酶1抗体
xy-3031R phospho-ASK1 (Thr845)磷酸化细胞凋亡信号调节激酶1抗体
xy-3033R phospho-ATF2 (Thr69/71)磷酸化活化复制因子2抗体
xy-3034R Phospho-ATP1A1 (Tyr10)磷酸化钠钾ATP酶蛋白a1抗体
xy-3035R Phospho-ATP1A1 (Ser16)磷酸化钠钾ATP酶蛋白a1抗体
xy-2745R Acetyl CoA Carboxylase乙酰辅酶A羧化酶抗体
xy-3036R Phospho-Acetyl Coenzyme A carboxylase alpha (Ser78)磷酸化乙酰辅酶A羧化酶抗体
xy-3038R Phospho-Ack1 (Tyr859 + 860)磷酸化Ack1抗体