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细胞因子产物DNA甲基化PCR芯片Cytokine Prod

uction DNA Methylation PCR Array
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  • Cytokine Production DNA Methylation PCR Array
  • 上海
  • 2026年01月23日
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      Cytokine Production DNA Methylation PCR Array

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      SAB

    Human Cytokine Production DNA Methylation PCR Array: EAHS-541Z
    The Human Cytokine Production EpiTect Methyl II Signature PCR Array profiles the promoter methylation status of a panel of 22 genes whose role in cytokine biosynthesis has been well documented. Profiling cellular or fresh tissue DNA samples with these arrays may help correlate CpG island methylation status with capacity of the resident immune or non-immune cells to produce and secrete cytokines. The results may also help provide insights into the molecular mechanisms and biological pathways behind immune disorders characterized by a lack or overabundance of cytokines in circulation. With a simple restriction enzyme digestion and real-time PCR, research studies can analyze the promoter methylation status of 22 different cytokine-producing genes with this DNA methylation PCR array.
    Both 96-well and 384-well ( 4 X 96 ) formats are available.
    The EpiTect Methyl II PCR Arrays use the MethylScreen™ Technology provided under license from Orion Genomics, LLC.
    T Cell Function Regulators: BCL10, BCL3, FOXP3, HMOX1, IL12A, MALT1, MAP3K7, SOD1, STAT5A, TRAF2, TRAF6.
    B Cell Function Regulators: BCL10, BCL3, INHA, INHBA, STAT5A.
    Transcriptional Regulators: BCL10, BCL3, FOXP3, GATA3, IRF1, SMAD3, STAT5A.
    Translational Regulators: BCL3, IGF2BP2.
    Environment & Intracellular Stimuli Responses: BCL10, BCL3, ELA2, FOXP3, GATA3, HMOX1, IL12A, INHA, INHBA, LTB, MALT1, MYD88, NOD1, SMAD3, SOD1, STAT5A, TLR2.
    Cytokine Production Signaling Molecules: BCL10, BCL3, FOXP3, HMOX1, INHA, INHBA, LTB, MALT1, MAP3K7, MYD88, NOD1, SMAD3, SOD1, STAT5A, TLR2, TRAF2, TRAF6.

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    • Methylation Profiling Using Methylated DNA Immunoprecipitation and Tiling Array Hybridization

      DNA methylation is an important epigenetic modification that regulates development and plays a role in the pathophysiology of many diseases. It is dynamically changed during germline development. Methylated DNA immunoprecipitation (MeDIP

    • DNA methylation

      of techniques have been developed. Most early studies used methylation sensitive restriction enzymes to digest DNA followed by Southern detection or PCR amplification. Recently, bisulfite reaction based methods have become very popular such as methylation

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