G蛋白偶联受体PCR芯片 384孔G Protein Cou

G蛋白偶联受体PCR芯片384孔 可全面检测370个编码最重要G蛋白偶联受体（GPCR）的基因。GPCR调控一系列正常的生物学过程或直接在病理过程中发挥作用，占已开发的药物靶点的30%。开发药物靶点筛选试验时，不仅要确定目标GPCR的表达，还要研究相关的GPCR的脱靶副作用。芯片包括神经递质受体，神经肽受体，荷尔蒙受体，趋化因子受体和细胞因子受体，脂信号通路受体，光敏复合物受体，气味分子受体和信息素受体，这些受体会被激活并发挥生物作用。受GPCR调控的正常的生物过程包括：行为和情绪调控（血清素，多巴胺，GABA，谷氨酸盐和其他神经递质受体），自主神经系统（交感神经系和副交感神经系）传送（血压，心跳，通过荷尔蒙受体的消化过程），视觉（类视紫红质视蛋白），嗅觉（气味分子的嗅觉受体，信息素的犁鼻器）。使用这一芯片试剂盒及配套试剂检测RNA实验标本，研究者可以简单准确，并且全面的检测和分析G蛋白偶联受体基因的表达。
Neurotransmitter Receptors:
Adenosine Receptors: ADORA1, ADORA2A, ADORA2B, ADORA3.
Adrenergic Receptors: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3.
Cannabinoid Receptors: CNR1, CNR2.
Dopamine Receptors: DRD1, DRD2, DRD3, DRD4, DRD5.
Gamma-Aminobutyric Acid (GABA) Receptors: GABBR1, GABBR2.
Muscarinic Cholinergic Receptors: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5.
Opioid Receptors: OGFR, OPRD1, OPRK1, OPRL1, OPRM1.
Ionotropic Glutamate Receptor: GRIK3.
Metabotropic Glutamate Receptors: GRM1, GRM2, GRM3, GRM4, GRM5, GRM6, GRM7, GRM8.
Serotonin (5-Hydroxytryptamine) Receptors: HTR1A, HTR1B, HTR1D, HTR1E, HTR1F, HTR2A, HTR2B, HTR2C, HTR3A, HTR3B, HTR4, HTR5A, HTR6, HTR7.
Neuropeptide Receptors:
Galanin Receptors: GALR1, GALR2, GALR3.
Hypocretin (Orexin) Receptors: HCRTR1, HCRTR2.
Neuromedin Receptors: NMBR, NMUR1, NMUR2.
Neuropeptide Receptors: NPBWR1, NPBWR2, NPFFR1, NPFFR2, NPSR1, NPY1R, NPY2R, NPY5R.
Neurotensin Receptors: NTSR1, NTSR2.
Tachykinin Receptors: TACR1, TACR2, TACR3.
Hormone Receptors:
Calcitonin Receptors: CALCR, CALCRL.
Cholecystokinin Receptors: CCKAR, CCKBR.
Corticotropin Releasing Hormone Receptors: CRHR1, CRHR2.
Glucagon-Like Peptide Receptors: GLP1R, GLP2R.
Melanin-Concentrating Hormone Receptors: MCHR1, MCHR2.
Melanocortin Receptors: MC1R, MC2R, MC3R, MC4R, MC5R.
Parathyroid Hormone Receptors: PTH1R, PTH2R.
Prokineticin Receptors: PROKR1, PROKR2.
Somatostatin Receptors: SSTR1, SSTR2, SSTR3, SSTR4, SSTR5.
Others: APLNR, EMR1, FSHR, GCGR, GHRHR, GHSR, GIPR, GNRHR, GRPR, LEPR, LHCGR, PRLHR, SCTR, TRHR, TSHR.
Orphan G Protein-Coupled Receptors: GPR1, GPR101, GPR110, GPR111, GPR112, GPR113, GPR114, GPR115, GPR116, GPR119, GPR12, O3FAR1, GPR123, GPR124, GPR125, GPR126, GPR128, GPR132, GPR133, GPR135, GPR139, GPR141, GPR142, GPR143, GPR144, GPR146, GPR148, GPR149, GPR15, GPR150, GPR151, GPR152, GPR153, GPR156, GPR157, GPR158, GPR160, GPR161, GPR162, GPR17, GPR171, GPR173, GPR174, GPR176, GPR179, GPR18, GPR182, GPR183, GPR19, GPR20, GPR21, GPR22, GPR25, GPR26, GPR27, GPR3, GPR31, GPR32, GPR34, GPR35, GPR37, GPR37L1, GPR39, GPR4, GPR44, GPR45, GPR50, GPR52, GPR55, GPR56, GPR6, GPR61, GPR62, GPR63, GPR64, GPR65, GPR68, GPR75, GPR77, GPR78, HCAR1, GPR82, GPR83, GPR84, GPR85, GPR87, GPR88, GPR97, GPR98, GPRC5A, GPRC5B, GPRC5C, GPRC5D, GPRC6A.
Angiogenesis & Vasoactivity:
Angiotensin II Receptors: AGTR1, AGTR2.
Arginine Vasopressin Receptors: AVPR1A, AVPR1B, AVPR2.
Bradykinin Receptors: BDKRB1, BDKRB2.
Brain-Specific Angiogenesis Inhibitors: BAI1, BAI2, BAI3.
Endothelin Receptors: EDNRA, EDNRB.
Natriuretic Peptide Receptors: NPR1, NPR2, NPR3.
Vasoactive Intestinal Peptide Receptors: VIPR1, VIPR2.
Inflammation and Immune System Regulation:
Complement Component Receptors: C3AR1, C5AR1.
Chemokine & Cytokine Receptors: CCBP2, CCR1, CCR10, CCR2, CCR3, CCR4, CCR5, CCR6, CCR7, CCR8, CCR9, CCRL1, CCRL2, CMKLR1, CX3CR1, CXCR3, CXCR4, CXCR5, CXCR6, CXCR7, CXCR1, CXCR2, XCR1.
Histamine Receptors: HRH1, HRH2, HRH3, HRH4.
Lipid Messenger Receptors:
Cysteinyl Leukotriene Receptors: CYSLTR1, CYSLTR2.
Free Fatty Acid Receptors: FFAR1, FFAR2, FFAR3.
Leukotriene B4 & Thromboxane Receptors: LTB4R, LTB4R2, TBXA2R.
Lysophosphatidic Acid Receptors: LPAR1, LPAR2, LPAR3, LPAR4, LPAR5.
Prostaglandin Receptors: PTGDR, PTGER1, PTGER2, PTGER3, PTGER4, PTGFR, PTGIR.
Sphingosine-1-Phosphate Receptors: S1PR1, S1PR2, S1PR3, S1PR4, S1PR5.
Growth Factor Receptors:
Frizzled Homologs: FZD1, FZD10, FZD2, FZD3, FZD4, FZD5, FZD6, FZD7, FZD8, FZD9.
Platelet-Derived Growth Factor Receptors: PDGFRB, PDGFRL.
Other G Protein Coupled Receptors:
Coagulation Factor II (Thrombin) Receptors: F2R, F2RL1, F2RL2, F2RL3.
Cadherin, EGF LAG Seven-Pass G-Type Receptors (Flamingo Homologs): CELSR1, CELSR2, CELSR3.
Formyl Peptide Receptors: FPR1, FPR2, FPR3.
Leucine-Rich Repeat-Containing G Protein-Coupled Receptors: LGR4, LGR5.
Latrophilins: LPHN1, LPHN2, LPHN3.
MAS-Related G-Protein Couple Receptors: MAS1, MRGPRD, MRGPRE, MRGPRF, MRGPRG, MRGPRX1, MRGPRX2, MRGPRX3, MRGPRX4.
Melatonin Receptors: MTNR1A, MTNR1B.
Opsins & Rhodopsin: OPN1SW, OPN3, OPN4, OPN5, RHO.
Purinergic (P2Y) Receptors: P2RY1, P2RY10, P2RY11, P2RY12, P2RY13, P2RY14, P2RY2, P2RY4, LPAR6, P2RY6, P2RY8.
Relaxin/Insulin-Like Family Peptide Receptors: RXFP1, RXFP2, RXFP3, RXFP4.
Sortilin-Related VPS10 Domain Containing Receptors: SORCS1, SORCS2, SORCS3.
Trace Amine Associated Receptors: TAAR1, TAAR2, TAAR5, TAAR6, TAAR9.
Others: ADCYAP1R1, BRS3, CASR, CD97, CRCP, DARC, ELTD1, GPBAR1, GPER, HCAR2, KISS1R, OXGR1, OXTR, PPYR1, PTAFR, QRFPR, RGR, RRH, SIGMAR1, SMO, SUCNR1, TM2D1, UTS2R, XPR1.