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P00343 Recombinant Human Pepti

dyl-prolyl Cis-trans Isomerase A/Cyclophilin A/CYPA 细胞因子/蛋白
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  • ¥312 - 9120
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  • P00343
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥9120.0
    规格:500ug产品价格:¥6240.0
    规格:50ug产品价格:¥936.0
    规格:10ug产品价格:¥312.0
    基本信息
    基因名
    别名Peptidyl-prolyl cis-trans isomerase A;PPIase A;Cyclophilin A;Cyclosporin A-binding protein;Rotamase A;SP18;PPIA;CYPA
    中文名称Recombinant Human Peptidyl-prolyl Cis-trans Isomerase A/Cyclophilin A/CYPA
    外观(性状)Supplied as a 0.2 μm filtered solution of PBS, 10%glycerol,pH7.4.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
    运输条件干冰运输
    背景说明Peptidyl-prolyl cis-trans isomerase A is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family,which catalyzes the cis-trans isomerization of proline imidic peptide bonds.Cyclophilin A regulate many biological processes,including intracellular signaling,transcription,inflammation,and apoptosis.Cyclophilin is also incorporated into many viruses,including HIV1,where it has been speculated to be involved in functions such as viral assembly and infectivity.The immunosuppressive activity of cyclosporins has been correlated with their ability to form complexes with cyclophilins that inhibit calcineurin phosphatase activity and prevent incorporation of cyclophilin into viral particles.The cyclosporin/cyclophilin complex selectively binds and inactivates calcineurin,making it a useful inhibitor for studying calcineurin activity.
    来源E.coli
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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    图标文献和实验
    相关实验
    • Periplasmic Chaperones Used to Enhance Functional Secretion of Proteins in E. coli

      , and two peptidyl-prolyl cis /trans isomerases with chaperone activity, FkpA and SurA. Here, we present a detailed protocol how to use this system for the bacterial secretion of recombinant proteins, including human EGF as a new example, and we give hints

    • Introduction of human 14-3-3 proteins

      The human and bovine 14-3-3 eta protein mRNAs are highly conservedEvolutionary conservation of the 14-3-3 proteinExpression and structural analysis of 14-3-3 proteinsCrystal structure of the zeta isoform of the 14-3-3 proteinStructure of a 14

    • Vectors and Strains for Expression

      include those that increase secretion of heterologous protein by overexpressing eukaryotic protein disulfide isomerase, and those that decrease hyperglycosylation or provide human-type glycosylation. This chapter also discusses methods to create multicopy

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