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- 详细信息
- 文献和实验
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥9120.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥6240.0 |
| 规格: | 50ug | 产品价格: | ¥936.0 |
| 规格: | 10ug | 产品价格: | ¥312.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Peptidyl-prolyl cis-trans isomerase A;PPIase A;Cyclophilin A;Cyclosporin A-binding protein;Rotamase A;SP18;PPIA;CYPA |
| 中文名称 | Recombinant Human Peptidyl-prolyl Cis-trans Isomerase A/Cyclophilin A/CYPA |
| 外观(性状) | Supplied as a 0.2 μm filtered solution of PBS, 10%glycerol,pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 运输条件 | 干冰运输 |
| 背景说明 | Peptidyl-prolyl cis-trans isomerase A is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family,which catalyzes the cis-trans isomerization of proline imidic peptide bonds.Cyclophilin A regulate many biological processes,including intracellular signaling,transcription,inflammation,and apoptosis.Cyclophilin is also incorporated into many viruses,including HIV1,where it has been speculated to be involved in functions such as viral assembly and infectivity.The immunosuppressive activity of cyclosporins has been correlated with their ability to form complexes with cyclophilins that inhibit calcineurin phosphatase activity and prevent incorporation of cyclophilin into viral particles.The cyclosporin/cyclophilin complex selectively binds and inactivates calcineurin,making it a useful inhibitor for studying calcineurin activity. |
| 来源 | E.coli |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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, and two peptidyl-prolyl cis /trans isomerases with chaperone activity, FkpA and SurA. Here, we present a detailed protocol how to use this system for the bacterial secretion of recombinant proteins, including human EGF as a new example, and we give hints
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Vectors and Strains for Expression
include those that increase secretion of heterologous protein by overexpressing eukaryotic protein disulfide isomerase, and those that decrease hyperglycosylation or provide human-type glycosylation. This chapter also discusses methods to create multicopy
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