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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20℃,2 years.(Avoid freeze/thaw cycles)
- 保质期:
Store at -20℃,2 years.(Avoid freeze/thaw cycles)
- 英文名:
TDSRCVIGLYHPPLQVY
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
10mg/5mg/1mg
| 规格: | 10mg | 产品价格: | ¥4290.0 |
|---|---|---|---|
| 规格: | 5mg | 产品价格: | ¥3070.0 |
| 规格: | 1mg | 产品价格: | ¥1230.0 |
| 基本信息 | |
| 产品类型 | 多肽 |
| CAS | No.127650-08-2 |
| 单字母序列 | LRAHAVDVNG-NH2 |
| 三字母序列 | Leu-Arg-Ala-His-Ala-Val-Asp-Val-Asn-Gly-NH2 |
| 别名 | Cadherin Peptide,avian;Cadherin-1 (76-85) aMide (chicken);N-Cadherin (76-85) aMide (chicken) |
| 分子式 | C44H75N17O13 |
| 分子量 | 1050.19 |
| 纯度 | ≥95% |
| 外观(性状) | 冻干粉;Lyophilized powder |
| 盐体系 | TFA盐;Trifluoroacetate salt |
| 来源 | 合成;Synthetic |
| 储存条件 | Store at -20℃,2 years.(Avoid freeze/thaw cycles) |
| 类别/标签 | 其他多肽(Other Peptides) |
| 规格 | This decapeptide resides within the first extracellular domain (EC1) of N-cadherin. It inhibits cadherin-mediated cell adhesion, compaction of eight-cell-stage mouse embryos and rat neurite outgrowth on astrocytes. In the presence of this peptide Ca2+-dependent cell aggregation of bovine brain microvessel endothelial cells is prevented. A putative application in creating channels for paracellular drug delivery across blood brain barriers has been proposed. |
| In Vitro | Cadherin Peptide, avian inhibits Ca2+-dependent reaggregation of BBMECs with an IC50 value of 450 μM. Cadherin Peptide, avian (60 min) dose-dependently inhibits BBMEC cell-cell adhesion. |
| 单位 | 瓶 |
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文献和实验TRAF‐Mediated TNFR‐Family Signaling
, such as TRANCE‐R and CD40, bind to TRAF6 and other TRAF proteins, activating various pathways including Src‐family kinases. IL‐1R and Toll‐like receptors are indirectly linked to TRAF6 through MyD88, Tollip, and IRAK.
的RNA与核酶放在一起,此时就不会出现以上的片段. 还发现3个核酶同时切割的效果明显大于单个核酶的效果,这可以用来对抗病毒的变异. Beck et al所设计的核酶针对HBV前基因组RNA的包装信号,他是一个高度保守的、茎环结构的顺式因子,在基因组中出现了2次,他对病毒的包装及反转录都起着很重要的作用. 根据这些特点被认为是比较理想的靶子. 竺来发et al设计针对HBcAg mRNA编码序列的核酶,在Mg2+存在下,将137 nt的核酸准确地了解得到97 nt和40 nt两个片段,可有效的剪切HBV
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