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文献和实验Enrichment and Characterization of Glycopeptide Epitopes from Complex Mixtures
in the enrichment and identification of glyco-antigens, particularly T-cell epitopes. Similarly, major advances have been made in the identification, isolation, and detailed characterization of prokaryotic and eukaryotic glycoproteins and glycopeptides
Quantitative proteomic measurements are of significant interest in studies aimed at discovering disease biomarkers and providing new insights into biological pathways. A quantitative cysteinyl-peptide enrichment technology
. This can be used to identify the amino acid and hence the peptide sequence, with the exception of isoleucine and leucine, which are identical in mass and therefore indistinguishable (103). Both y- and b-type ions can also eliminate NH3 (-17 Da), H2 O (-18 Da
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