- ￥2508
- BioLegend-HK
- 352909
- 美国
- 2025年07月15日
- 免疫荧光，流式
- 小鼠
- 人
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- 抗体名：
PE/Cyanine7 anti-human EGFR
- 抗体英文名：
PE/Cyanine7 anti-human EGFR
- 应用范围：
免疫荧光，流式
- 宿主：
小鼠
- 供应商：
上海善然生物
- 库存：
现货
- 抗原来源：
小鼠
- 保质期：
2-3年左右
- 适应物种：
人
- 标记物：
PE/Cyanine7
- 克隆性：
单克隆
- 保存条件：
2-8度
- 形态：
液体
- 规格：
25 tests
PE/Cyanine7 anti-human EGFR Antibody
AY13
Catalog# / Size 352909 / 25 tests
352910 / 100 tests
Clone
Regulatory Status RUO
Other Names Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, HER1
Isotype Mouse IgG1, κ
Description Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein and member of the
protein kinase superfamily that regulates cell growth and differentiation. EGFR binds EGF,
TGF-α, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30, and vaccinia
virus growth factor - all members of the EGF family. Ligand binding induces EGFR
dimerization and autophosphorylation, initiating the MAPK, Akt, and JNK signaling pathways.
EGFR is expressed by epithelial and endothelial cells and is frequently expressed by epithelial
carcinomas.
Product Details
Verified Reactivity Human
Antibody Type Monoclonal
Host Species Mouse
Immunogen Non-small cell lung cancer (NSCLC) cell line NCI-H322
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under
optimal conditions.
Concentration Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our
Certificate of Analysis online tool.)
Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C, and protected from
prolonged exposure to light. Do not freeze
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EGFR and Tumor Suppressor Function in Brain Cancer Development
of a conditional firefly luciferase transgene provides a means to monitor tumor initiation and growth noninvasively by bioluminescence imaging. The tumors that are generated in this model share numerous histopathological features with human GBMs. We provide
The EGFR Pathway as an Example for Genotype: Phenotype Correlation in Tumor Genes
to be determinants of response to new drugs that inhibit EGFR. We describe the correlation between the EGFR genotype, including the KRAS mutation, and the consequences of the resulting genotype for anti-EGFR therapy in colorectal cancer.
In Vivo Imaging of the Dynamics of Different Variants of EGFR in Glioblastomas
with the fusion of a bioluminescent–fluorescent marker. This unit describes a protocol for simultaneously imaging EGFR activity and progression of GBM in a mouse model. Human glioma cells transduced with lentiviral vectors bearing different combinations
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