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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
齐源
- 库存:
868
- 靶点:
CD40
- 级别:
CD40 Antibody
- 目录编号:
CD40 Antibody
- 克隆性:
单克隆
- 抗原来源:
大鼠
- 保质期:
CD40 Antibody
- 抗体英文名:
Alexa Fluor® 647 anti-mouse CD40 Antibody
- 抗体名:
CD40 Antibody
- 标记物:
CD40 Antibody
- 宿主:
大鼠
- 适应物种:
小鼠
- 免疫原:
CD40 Antibody
- 亚型:
CD40 Antibody
- 形态:
CD40 Antibody
- 应用范围:
FC
- 保存条件:
2-8℃
- 浓度:
0.5 mg/ml
- 规格:
25 µg/100 µg
| 规格: | 25 µg | 产品价格: | ¥1800.0 |
|---|---|---|---|
| 规格: | 100 µg | 产品价格: | ¥5000.0 |
Description :CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of thetumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelialcells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switchingand, in combination with other signals such as IL-4, protects B cells from surface Ig-inducedapoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), whichis expressed on activated T cells, is important in costimulation and immune regulation.
Verified Reactivity :Mouse
Antibody Type :Monoclonal
Host Species :Rat
Immunogen :Recombinant mouse CD40 protein
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation :The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647under optimal conditions.
Concentration :0.5 mg/ml
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application :FC - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flowcytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg permillion cells in 100 µl volume. It is recommended that the reagent be titrated for optimalperformance for each application.
* Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm.
Excitation Laser :Red Laser (633 nm)
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文献和实验1. Hasbold J, et al. 1994. Eur. J. Immunol. 24:1835.
2. Bourgeois C, et al. 2002. Science 297:2060.
Product Citations:
1. Park HB, et al. 2020. Oncoimmunology. 9:1772663. PubMed
2. Hwang BJ, et al. 2019. Oncogene. 38:7491. PubMed
3. Fontana C, et al. 2016. J Biol Chem. 291: 7727-7741. PubMed
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