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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
齐源
- 库存:
999
- 靶点:
CD206 (MMR)
- 级别:
CD206 (MMR) Antibody
- 目录编号:
CD206 (MMR) Antibody
- 克隆性:
单克隆
- 抗原来源:
小鼠
- 保质期:
CD206 (MMR) Antibody
- 抗体英文名:
Cyanine7 anti-human CD206 (MMR) Antibody-APC
- 抗体名:
CD206 (MMR) Antibody
- 标记物:
APC
- 宿主:
小鼠
- 适应物种:
人
- 免疫原:
CD206 (MMR) Antibody
- 亚型:
CD206 (MMR) Antibody
- 形态:
CD206 (MMR) Antibody
- 应用范围:
FC
- 保存条件:
2-8℃
- 浓度:
CD206 (MMR) Antibody
- 规格:
25 tests/100 tests
| 规格: | 25 tests | 产品价格: | ¥2400.0 |
|---|---|---|---|
| 规格: | 100 tests | 产品价格: | ¥5200.0 |
Description :Macrophage mannose receptor (MMR) is a 162-175 kD type I membrane protein also known asCD206, MRC1, or mannose receptor (MR). It is a pattern recognition receptor (PRR) thatbelongs to C-type lectin superfamily. MMR is expressed on macrophages, dendritic cells, andhepatic or lymphatic endothelial cells, but not on monocytes. MMR recognizes a range ofmicrobial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine. MMR mediatesendocytosis and phagocytosis, induces activation of macrophages and antigen presentation,plays an important role in host defense, and provides a link between innate and adaptiveimmunity.
Verified Reactivity :Human
Antibody Type :Monoclonal
Host Species :Mouse
Immunogen :Purified human mannose receptor
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation :The antibody was purified by affinity chromatography, and conjugated with APC/Cyanine7 underoptimal conditions.
Concentration :Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application :FC - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in100 µl staining volume or 5 µl per 100 µl of whole blood.
Excitation Laser :Red Laser (633 nm)
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文献和实验1. Noorman F, et al. 1997. J. Leukocyte Biol. 61:63. (WB, IHC, Block)
2. Barrett-Bergshoeff M, et al. 1997. Thromb Haemost. 77:718. (Block)
3. Kato M, et al. 2007. J. Immunol. 179:6052. (IF)
Product Citations:
1. Nikonova A, et al. 2020. EBioMedicine. 54:102734. PubMed
2. Higham A, et al. 2021. Cells. 11:. PubMed
3. Y C, et al. 2016. J Immunol . 195: 4884-91. PubMed
4. Nam J, et al. 2021. Adv Sci (Weinh). 2002577:8. PubMed
5. Zhang S, et al. 2020. Front Immunol. 1.757638889. PubMed
6. Isik G, et al. 2013. PLoS One. 8:60126. PubMed
7. Muir LA, et al. 2022. JCI Insight. 7:. PubMed
8. Mehta AK, et al. 2021. Nat Cancer. 2:66. PubMed
9. Castellaro AM, et al. 2019. Cancers (Basel). 11:. PubMed
10. Norton S, et al. 2016. Clin Transl Immunology. 5: e76. PubMed
11. Sabree SA, et al. 2021. J Immunother Cancer. 9: . PubMed
12. Tamò L, et al. 2021. Int J Mol Sci. 22:00. PubMed
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