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- 文献和实验
- 技术资料
- 供应商:
齐源
- 库存:
999
- 靶点:
CD206 (MMR)
- 级别:
CD206 (MMR) Antibody
- 目录编号:
CD206 (MMR) Antibody
- 克隆性:
单克隆
- 抗原来源:
小鼠
- 保质期:
CD206 (MMR) Antibody
- 抗体英文名:
Cyanine5.5 anti-human CD206 (MMR) Antibody-PerCP
- 抗体名:
CD206 (MMR) Antibody
- 标记物:
PerCP
- 宿主:
小鼠
- 适应物种:
人
- 免疫原:
CD206 (MMR) Antibody
- 亚型:
CD206 (MMR) Antibody
- 形态:
CD206 (MMR) Antibody
- 应用范围:
FC
- 保存条件:
2-8℃
- 浓度:
CD206 (MMR) Antibody
- 规格:
25 tests/100 tests
| 规格: | 25 tests | 产品价格: | ¥3000.0 |
|---|---|---|---|
| 规格: | 100 tests | 产品价格: | ¥6500.0 |
Description :Macrophage mannose receptor (MMR) is a 162-175 kD type I membrane protein also known asCD206, MRC1, or mannose receptor (MR). It is a pattern recognition receptor (PRR) thatbelongs to C-type lectin superfamily. MMR is expressed on macrophages, dendritic cells, andhepatic or lymphatic endothelial cells, but not on monocytes. MMR recognizes a range ofmicrobial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine. MMR mediatesendocytosis and phagocytosis, induces activation of macrophages and antigen presentation,plays an important role in host defense, and provides a link between innate and adaptiveimmunity.
Verified Reactivity :Human
Antibody Type :Monoclonal
Host Species :Mouse
Immunogen :Purified human mannose receptor
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation :The antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5under optimal conditions.
Concentration :Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application :FC - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in100 µl staining volume or 5 µl per 100 µl of whole blood.
* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.
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文献和实验1. Noorman F, et al. 1997. J. Leukocyte Biol. 61:63. (WB, IHC, Block)
2. Barrett-Bergshoeff M, et al. 1997. Thromb Haemost. 77:718. (Block)
3. Kato M, et al. 2007. J. Immunol. 179:6052. (IF)
Product Citations:
1. Leach SM, et al. 2020. Cell Rep. 33:108337. PubMed
2. Mulder K, et al. 2021. Immunity. 54(8):1883-1900.e5. PubMed
3. Li C, et al. 2015. PLoS One. 10: e0141817. PubMed
4. Ray SC, et al. 2018. J Immunol. 200:3568. PubMed
5. Wu X, et al. 2020. Front Immunol. 1.922222222. PubMed
6. Hartwig T et al. 2017. Molecular cell. 65(4):730-742 . PubMed
7. Vierboom MPM, et al. 2021. Cell Reports Medicine. 2(1):100185. PubMed
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69、CD38 等活化指标,及 IFN-γ、IL-4、IL17A 等细胞因子,则需要设置同型对照,实现阴阳性细胞群的良好区分。 CD4 CD25 (2)在某些特殊情况下,如单核细胞被 PE/Cyanine 7、APC/Cyanine 7 等串联染料标记的抗体染色时,使用同型对照抗体是十分有必要的。单核细胞一般倾向于与 Cyanine7 等染料非特异性结合,使用同型对照抗体有助于获得理想结果。 (3)不清楚抗原表达情况的时候,一定要使用同型对照来界定阴性细胞群。 (4)胞内染色时
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