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- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
CD107a (LAMP-1)
- 级别：
CD107a (LAMP-1) Antibody
- 目录编号：
CD107a (LAMP-1) Antibody
- 克隆性：
单克隆
- 抗原来源：
大鼠
- 保质期：
CD107a (LAMP-1) Antibody
- 抗体英文名：
Alexa Fluor® 594 anti-mouse CD107a (LAMP-1) Antibody
- 抗体名：
CD107a (LAMP-1) Antibody
- 标记物：
CD107a (LAMP-1) Antibody
- 宿主：
大鼠
- 适应物种：
小鼠
- 免疫原：
CD107a (LAMP-1) Antibody
- 亚型：
CD107a (LAMP-1) Antibody
- 形态：
CD107a (LAMP-1) Antibody
- 应用范围：
IHC-F
- 保存条件：
2-8℃
- 浓度：
0.5 mg/ml
- 规格：
100 µg
Description ：CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation,CD107a is transferred to the cell membrane surface of activated platelets, activatedlymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107ahas been suggested to play a role in the protection of lysosomal membrane from lysosomalhydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediatesautoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surfaceexpression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.
Verified Reactivity ：Mouse
Antibody Type ：Monoclonal
Host Species ：Rat
Immunogen ：This monoclonal antibody was raised against NIH/3T3 mouse embryonic fibroblast tissue culturecell membranes. It has been mapped to the N-terminus of LAMP-1.
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation ：The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 594under optimal conditions.
Concentration ：0.5 mg/ml
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：IHC-F - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by immunohistochemical staining on frozen tissuesections. For immunohistochemistry, a concentration range of 2.5 - 10 µg/ml is suggested. It isrecommended that the reagent be titrated for optimal performance for each application.
* Alexa Fluor® 594 has an excitation maximum of 590 nm, and a maximum emission of 617 nm.
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文献和实验保持优异的水溶性，为该波段最亮的橙色荧光染料。例如：同等的标记程度下，CF543 标记的羊抗鼠IgG抗体的亮度高于用Alexa Fluor 546 标记的2~10倍。CF 555、AlexaFluor 555、Tetramethylrhodamine(TAMRA) 等匹配Cy3滤光片的橙色荧光染料；红色（568-594nm处激发）CF 568、Alexa Fluor® 568,ATTO 565, Rhodamine Red等568nm处红色荧光染料；CF 568染料耐光性最好；高效水溶
CST 抗体 9 月特惠｜购买任意 CST 抗体，+168 元即可入手 25μl 标签 / 内参抗体
HRP、Alexa Fluor® 488、Alexa Fluor® 594 等多种标记一抗可选。 热门可选产品参考 货号 产品名称 类型 加价购价格 S0B0005-25u1 B-actin Rabbit mAb (SDT-RO15) 裸抗 168 元 S0B0004-25u1 B-tubulin Recombinant Rabbit mAb (SDT-RO14) 裸抗 168 元 S0B0383-25u1 S-RMab® Myc tag Recombinant Rabbit
，耐光，水溶性好，确保了CF 543染料与抗体的耦联物保持优异的水溶性，为该波段最亮的橙色荧光染料。例如：同等的标记程度下，CF 543标记的羊抗鼠IgG抗体的亮度高于用Alexa Fluor 546 标记的2~10倍。 CF 555、Alexa Fluor 555、Tetramethylrhodamine (TAMRA) 等匹配Cy3滤光片的橙色荧光染料。 4、红色（568-594nm处激发） CF 568、Alexa Fluor® 568, ATTO 565
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