GoInVivo™ Purified 抗小鼠 CD274 (

GoInVivo™ Purified anti-mouse CD274 (B7-H1, PD-L1) Antibody详细如下：   
Description ：CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type Itransmembrane protein and a member of the B7 family within the immunoglobulin receptorsuperfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activatedendothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1with PD-1 plays an important role in the inhibition of T cell responses. Other studies haveshown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 isinvolved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, inan IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cellproliferation and cytokine production.

Verified Reactivity ：Mouse
Antibody Type ：Monoclonal
Host Species ：Rat
Formulation ：0.2 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxinlevel is <1.0 EU/mg of the protein. (<0.1 pg/µg of the protein) as determined by the LAL test.
Preparation ：The GoInVivo™ antibody was purified by affinity chromatography
Concentration ：The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and3 mg/mL.
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C. This GoInVivo™ solutioncontains no preservative; handle under aseptic conditions.

Application ：FC - Quality tested
Block - Reported in the literature, not verified in house

Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cellsin 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated foroptimal performance for each application.