抗人CCX-CKR（CCRL1）荧光标记APC 抗体

anti-human CCX-CKR (CCRL1) Antibody-APC详细如下：

Description ：Human CCX-CKR, also known as CCRL1, is a 40 kD, G-protein-coupled, seventransmembrane receptor. CCRL1 is a decoy receptor for CCL2, CCL8, CCL13, CCL19, CCL21and CCL25 that regulates chemotaxis of lymphocytes and cancer cells. Chemokine binding byCCX-CKR causes its internalization, reducing levels of available chemokine, and thusregulating migration of lymphocytes and cancerous cells. CCX-CKR is expressed by stromalcells of skin-draining lymph nodes, thymic epithelial cells, and immature dendritic cells (DCs). Alow CCX-CKR expression in tumor cells correlates with a poor survival rate of breast cancerpatients.

Verified Reactivity ：Human

Antibody Type ：Monoclonal

Host Species ：Mouse

Immunogen ：Full length CCX-CKR cDNA

Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation ：The antibody was purified by affinity chromatography and conjugated with APC under optimalconditions.

Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)

Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.

Application ：FC - Quality tested

Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser ：Red Laser (633 nm)

Application Notes ：Additional reported applications for the relevant formats include: immunoprecipitation of CCX-CKRfrom cell lysates , induction of CCX-CKR internalization and immunofluorescence . 13E11recognizes an epitope located within the first 14 amino acids of CCX-CKR.