mTOR,cyclin B1,Bcl⁃2 and levels of p⁃PI3K,p⁃Akt and p⁃mTOR were decreased,and the mRNA and protein cated serum can increase chemosensitivity ofhuman gastric cancerresistant cellline SGC7901/ADR,whichmay be related to inhibition ofPI3K/AKT/mTOR pathway,inhibitionofcyclin B1,Bcl⁃2expression,andpromotionof Bax andp21 expression. [Key words]Banxia Xiexin Decoction;gastric cancer;phosphoinositol 3kinase;protein kinase B;mammaliantargetofrapamycin;chemosensitivity
MHCC97H-LUC人高转移人肝癌细胞-荧光素酶标记
mTOR,cyclin B1,Bcl⁃2 and levels of p⁃PI3K,p⁃Akt and p⁃mTOR were decreased,and the mRNA and protein cated serum can increase chemosensitivity ofhuman gastric cancerresistant cellline SGC7901/ADR,whichmay be related to inhibition ofPI3K/AKT/mTOR pathway,inhibitionofcyclin B1,Bcl⁃2expression,andpromotionof Bax andp21 expression. [Key words]Banxia Xiexin Decoction;gastric cancer;phosphoinositol 3kinase;protein kinase B;mammaliantargetofrapamycin;chemosensitivity